Environmental Chemicals, Enzyme Function and Human Disease.
by
Symposium, CIBA Foundation.
Title
:
Environmental Chemicals, Enzyme Function and Human Disease.
Author
:
Symposium, CIBA Foundation.
ISBN
:
9780470718278
Personal Author
:
Symposium, CIBA Foundation.
Edition
:
1st ed.
Physical Description
:
1 online resource (392 pages)
Series
:
Novartis Foundation Symposia ; v.868
Novartis Foundation Symposia
Contents
:
Environmental Chemicals Enzyme Function and Human Disease -- Contents -- Chairman's introduction -- The role of the drug-metabolizing enzymes -- Discussion -- The influence of inducers on drug-metabolizing enzyme activity and on formation of reactive drug metabolites in the liver -- Discussion -- Effects of inducers and inhibitors on drug-metabolizing enzymes and on drug toxicity in extrahepatic tissues -- Discussion -- Induction of enzymes involved in DNA repair and mutagenesis -- Discussion -- Induction of drug-metabolizing enzymes by polycyclic aromatic hydrocarbons: mechanisms, and some implications in environmental health research -- Discussion -- Induction of drug-metabolizing enzymes by phenobarbitone: structural and biochemical aspects -- Discussion -- Substrate-dependent irreversible inactivation of cytochrome P-450: conversion of its haem moiety into modified porphyrins -- Discussion -- General Discussion I -- Regulation of human drug metabolism by dietary factors -- Discussion -- Influence of foreign compounds on formation and disposition of reactive metabolites -- Discussion -- Pharmacokinetic factors governing the steady-state concentrations of foreign chemicals and their metabolites -- Discussion -- Toxicological implications of polymorphic drug metabolism -- Discussion -- Immunologically mediated toxicity -- Discussion -- Toxicological significance of liver hypertrophy produced by inducers of drug-metabolizing enzymes -- Discussion -- The influence of nutrition and inducers on mechanisms of toxicity in humans and animals -- Discussion -- Influence of environmental chemicals on drug therapy in humans: studies with contraceptive steroids -- Discussion -- General Discussion II -- Vitamin D metabolism in patients treated with phenytoin and phenobarbitone -- Discussion -- Chemical disease in humans: problems in comparative toxicology.
Discussion -- Implications for future studies in humans -- Final General Discussion -- Index of Contributors -- Subject Index.
Local Note
:
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2017. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
Subject Term
:
Biotransformation (Metabolism) -- Congresses.
Drugs -- Metabolism -- Congresses.
Enzyme induction -- Congresses.
Toxicology -- Congresses.
Genre
:
Electronic books.
Added Author
:
Lastciba Foundation Symposium,.
Electronic Access
:
Library | Material Type | Item Barcode | Shelf Number | Status |
---|
IYTE Library | E-Book | 1228829-1001 | RA1191 -- .S95 1979 EB | Ebrary E-Books |