Research Briefings 1986 -- Copyright -- Preface -- Contents -- Research Briefing Panel on Science of Interfaces and Thin Films -- Report of the Research Briefing Panel on Science of Interfaces and Thin Films -- DEFINITIONS, PROPERTIES, AND BEHAVIORS -- RESEARCH ISSUES -- Characterization of Interfaces and Thin Films -- Preparative Techniques -- Properties of Matter in Two Dimensions -- Interface Reactivity -- Biocompatible Surfaces and Interfaces -- APPLICATIONS -- Microelectronics in Communications and Computers -- Control of Corrosion, Friction, and Wear -- Structural Materials -- Energy Production -- National Security -- MANAGEMENT ISSUES -- Report of the Research Briefing Panel on Decision Making and Problem Solving -- Research Briefing Panel on Decision Making and Problem Solving -- Report of the Research Briefing Panel on Decision Making and Problem Solving -- INTRODUCTION -- DECISION MAKING -- SEU Theory -- The Limits of Rationality -- Limited Rationality in Economic Theory -- The Theory of Games -- Empirical Studies of Choice Under Uncertainty -- Methods of Empirical Research -- PROBLEM SOLVING -- Contemporary Problem-Solving Theory -- Expert Systems in Artificial Intelligence -- Dealing with Ill-Structured Problems -- Setting the Agenda and Representing a Problem -- Computation as Problem Solving -- Extensions of Theory -- Decision Making over Time -- Aggregation -- Organizations -- Learning -- CURRENT RESEARCH PROGRAMS -- RESEARCH OPPORTUNITIES: SUMMARY -- Report of the Research Briefing Panel on Protein Structure and Biological Function -- Research Briefing Panel on Protein Structure and Biological Function -- Report of the Research Briefing Panel on Protein Structure and Biological Function -- INTRODUCTION -- RESEARCH GOALS -- The Folding Problem -- Protein Stability -- Ligand Binding -- Signal Transmission.

RECENT ADVANCES IN KNOWLEDGE -- TECHNOLOGICAL ADVANCES -- X-Ray Diffraction -- Area Detectors -- Synchrotron X-Ray Sources -- Computing and Graphics -- Neutron Diffraction -- Crystallization -- Nuclear Magnetic Resonance -- Synthesis of Proteins -- Chemical Synthesis -- Biological Synthesis -- Theory -- BOTTLENECKS AND RECOMMENDATIONS -- Report of the Research Briefing Panel on Prevention and Treatment of Viral Diseases -- Research Briefing Panel on Prevention and Treatment of Viral Diseases -- Report of the Research Briefing Panel on Prevention and Treatment of Viral Diseases -- INTRODUCTION -- Prevention of Viral Diseases -- Treatment of Viral Diseases -- Target Viral Diseases -- RECENT ADVANCES IN MOLECULAR VIROLOGY -- THE STRUCTURE OF VIRUS PARTICLES -- SPECIFIC STRATEGIES FOR PREVENTING VIRAL DISEASES -- Genetically Modified Live Viruses -- The Use of Virus Vectors -- Purified Viral Proteins as Antigens for Vaccines -- Development of Technologies for Enhancing Immunogenicity -- STRATEGIES FOR THE TREATMENT OF VIRAL DISEASES -- The Viral Multiplication Cycle -- Strategies for the Expression of Viral Genetic Information -- Strategies for the Replication of Viral Genetic Material -- Opportunities for Interfering with the Viral Growth Cycle -- Inhibition of Virus-Encoded Enzymes -- Inhibition of Interactions of Viral and Host Cell Proteins with Regulatory Sequences in Viral Genomes -- Interference with Messenger RNA Function -- The Target-Cell Approach -- THE NEED FOR IMPROVED TECHNIQUES TO DIAGNOSE VIRAL INFECTIONS -- SELECTED OPPORTUNITIES AMONG VIRAL DISEASES -- Acquired Immune Deficiency Syndrome (AIDS) -- Influenza Viruses -- Herpes Simplex Viruses (HSV) 1 and 2 -- Hepatitis B Virus (HBV) -- Rotaviruses -- Other Viruses -- IMPLEMENTING STRATEGIES FOR DEVELOPMENT OF NEW VACCINES AND ANTIVIRALS.

BENEFITS OF A NATIONAL EFFORT ON VACCINES AND ANTIVIRALS -- SUMMARY AND CONCLUSIONS.