A Master Regulator of Oxidative Stress - The Transcription Factor Nrf2
by
Jose Antonio Morales-Gonzalez
Title
:
A Master Regulator of Oxidative Stress - The Transcription Factor Nrf2
Author
:
Jose Antonio Morales-Gonzalez
ISBN
:
62743
9789535128373
9789535128380
Personal Author
:
Jose Antonio Morales-Gonzalez
Publication Information
:
IntechOpen 2016
Physical Description
:
1 electronic resource (210 p.)
Abstract
:
Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. Therefore, the efforts of various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases, for example, cancer, where it would be important to regulate Nrf-2 in order for it to activate apoptosis pathways in cancerogenous cells, or in neurodegenerative diseases where cell death is predominant, it would be important for Nrf-2 to activate antiapoptotic pathways.
Added Author
:
Eduardo Osiris Madrigal-Santillan
Angel Morales-Gonzalez
Electronic Access
:
Library | Material Type | Item Barcode | Shelf Number | Status |
---|
IYTE Library | E-Book | 2194868-1001 | XX(2194868.1) | DOAB E-Books |