Loki's villainous machinations pit Spider-Man and the X-Men against unfamiliar foes! Spidey has his hands full with powerful sparring partners like Graviton, Magneto and the terrifying Tri-Sentinel — but when a cosmic upgrade boosts his powers, the ruthless Doctor Doom puts the web-slinger in his crosshairs! Meanwhile, the X-Men take on the Mandarin — and Psylocke is transformed! Teeth meet claws when Wolverine battles Tiger Shark! Nitro and the Vulture target the New Mutants' Rusty and Skids! And it's tyrant vs. trickster when Apocalypse faces Loki! Plus: Alpha Flight tackles an unholy alliance of super villains — including Nekra, the Scorpion and the Owl!