Targeted Antibody Blocking by a Dual-Functional Conjugate of Antigenic Peptide and Fc-III Mimetics (DCAF)
by
 
Bai, Xue

Title
: 
Targeted Antibody Blocking by a Dual-Functional Conjugate of Antigenic Peptide and Fc-III Mimetics (DCAF)

Author
: 
Bai, Xue

Personal Author
: 
Bai, Xue

Publication Information
: 
Cambridge, MA MyJoVE Corp 2016

Physical Description
: 
online resource (579 seconds)

Series
: 
Immunology and Infection

General Note
: 
Title from resource description page

Abstract
: 
Development of a dual-functional conjugate of antigenic peptide and Fc-III mimetics (DCAF) is novel for the elimination of harmful antibodies. Here, we describe a detailed protocol for the synthesis of DCAF1 molecule, which can selectively block 4G2 antibody to eliminate antibody dependent enhancement effect during Dengue virus infection.

Reading Level
: 
For undergraduate, graduate, and professional students

Subject Term
: 
Immunology and Infection

Electronic Access
: 
https://www.jove.com/t/60063


LibraryMaterial TypeItem BarcodeShelf NumberStatus
IYTE LibraryOnline Video2249350-1001XX(2249350.1)JoVe Video Online