Hepatocyte-specific Ablation in Zebrafish to Study Biliary-driven Liver Regeneration
by
Choi, Tae-Young
Title
:
Hepatocyte-specific Ablation in Zebrafish to Study Biliary-driven Liver Regeneration
Author
:
Choi, Tae-Young
Personal Author
:
Choi, Tae-Young
Publication Information
:
Cambridge, MA MyJoVE Corp 2016
Physical Description
:
online resource (494 seconds)
Series
:
Developmental Biology
General Note
:
Title from resource description page
Abstract
:
To help assess the molecular mechanisms underlying zebrafish biliary-driven liver regeneration, we established a liver injury model in which the nitroreductase-expressing hepatocytes are genetically ablated upon metronidazole treatment. In this protocol, we describe how to adeptly manipulate, monitor and analyze hepatocyte ablation and biliary-driven liver regeneration.
Reading Level
:
For undergraduate, graduate, and professional students
Subject Term
:
Developmental Biology
Electronic Access
:
Library | Material Type | Item Barcode | Shelf Number | Status |
---|
IYTE Library | Online Video | 2254627-1001 | XX(2254627.1) | JoVe Video Online |