Examining BCL-2 Family Function with Large Unilamellar Vesicles
by
 
Asciolla, James J.

Title
Examining BCL-2 Family Function with Large Unilamellar Vesicles

Author
Asciolla, James J.

Personal Author
Asciolla, James J.

Publication Information
Cambridge, MA MyJoVE Corp 2016

Physical Description
online resource (515 seconds)

Series
Biology

General Note
Title from resource description page

Abstract
Biochemically-defined large unilamellar vesicles (LUVs) are a convenient model system to analyze BCL-2 family interactions with immediate implications in better understanding the mitochondrial pathway of apoptosis. A method to produce LUVs, along with standard BCL-2 family protein combinations and controls to examine LUV permeabilization, are presented.

Reading Level
For undergraduate, graduate, and professional students

Subject Term
Biology

Electronic Access
https://www.jove.com/t/4291


LibraryMaterial TypeItem BarcodeShelf NumberStatus
IYTE LibraryOnline Video2256744-1001XX(2256744.1)JoVe Video Online