Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding
by
Almond, David
Title
:
Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding
Author
:
Almond, David
Personal Author
:
Almond, David
Publication Information
:
Cambridge, MA MyJoVE Corp 2016
Physical Description
:
online resource (650 seconds)
Series
:
Immunology and Infection
General Note
:
Title from resource description page
Abstract
:
The crown region of different V3 loop sequences of the surface envelope glycoprotein (gp120) of HIV-1 can be structurally characterized in many cases by in silico folding of positions 10 to 22 of the loop using a state-of-the-art ab initio folding algorithm. Here we demonstrate the folding and evaluation of this region of the V3 loop from the R2 strain of HIV-1, a uniquely neutralization sensitive strain with puzzling functional properties.
Reading Level
:
For undergraduate, graduate, and professional students
Subject Term
:
Immunology and Infection
Electronic Access
:
Library | Material Type | Item Barcode | Shelf Number | Status |
---|
IYTE Library | Online Video | 2257977-1001 | XX(2257977.1) | JoVe Video Online |