Front Cover -- From Molecules to Networks: An Introduction to Cellular and Molecular Neuroscience -- Copyright Page -- Full Contents -- Contributors -- Preface -- Chapter 1. Cellular Components of Nervous Tissue -- The Neuron -- The Neuroglia -- The Cerebral Vasculature -- Chapter 2. Subcellular Organization of the Nervous System: Organelles and Their Functions -- Axons and Dendrites: Unique Structural Components of Neurons -- Protein Synthesis in Nervous Tissue -- The Cytoskeletons of Neurons and Glial Cells -- Molecular Motors in the Nervous System -- Building and Maintaining Nervous System Cells -- Chapter 3. Brain Energy Metabolism -- Energy Metabolism of the Brain as a Whole Organ -- Tight Coupling of Neuronal Activity, Blood Flow, and Energy Metabolism -- Energy-Producing and Energy-Consuming Processes in the Brain -- Brain Energy Metabolism at the Cellular Level -- Glutamate and Nitrogen Metabolism: A Coordinated Shuttle Between Astrocytes and Neurons -- The Astrocyte-Neuron Metabolic Unit -- Chapter 4. Electrotonic Properties of Axons and Dendrites -- Spread of Steady-State Signals -- Spread of Transient Signals -- Electrotonic Properties Underlying Propagation in Axons -- Electrotonic Spread in Dendrites -- Dynamic Properties of Passive Electrotonic Structure -- Relating Passive to Active Potentials -- Chapter 5. Membrane Potential and Action Potential -- The Membrane Potential -- The Action Potential -- Chapter 6. Molecular Properties of Ion Channels -- Families of Ion Channels -- Channel Gating -- Ion Permeation -- Ion Channel Distribution -- Summary -- Chapter 7. Dynamical Properties of Excitable Membranes -- The Hodgkin-Huxley Model -- A Geometric Analysis of Excitability -- Chapter 8. Release of Neurotransmitters -- Organization of the Chemical Synapse -- Excitation-Secretion Coupling.

The Molecular Mechanisms of the Nerve Terminal -- Quantal Analysis -- Short-Term Synaptic Plasticity -- Chapter 9. Pharmacology and Biochemistry of Synaptic Transmission: Classic Transmitters -- Diverse Modes of Neuronal Communication -- Chemical Transmission -- Classic Neurotransmitters -- Summary -- Chapter 10. Nonclassic Signaling in the Brain -- Peptide Neurotransmitters -- Neurotensin as an Example of Peptide Neurotransmitters -- Unconventional Transmitters -- Synaptic Transmitters in Perspective -- Chapter 11. Neurotransmitter Receptors -- Ionotropic Receptors -- G Protein-Coupled Receptors -- Chapter 12. Intracellular Signaling -- Signaling Through G-Protein-Linked Receptors -- Modulation of Neuronal Function by Protein Kinases and Phosphatases -- Chapter 13. Regulation of Neuronal Gene Expression and Protein Synthesis -- Intracellular Signaling Affects Nuclear Gene Expression -- Role of cAMP and Ca2+ in the Activation Pathways of Transcription -- Summary -- Chapter 14. Mathematical Modeling and Analysis of Intracellular Signaling Pathways -- Methods for Modelling Intracellular Signaling Pathways -- General Issues in the Modeling of Biochemical Systems -- Specific Modeling Methods -- Summary -- Chapter 15. Cell-Cell Communication: An Overview Emphasizing Gap Junctions -- Chemical and Electrical Synapses Differ in Functional Characteristics -- Biophysical and Pharmacological Properties of Gap Junctions in the Nervous System -- Role of Gap Junctions in Functions of Nervous Tissue -- Gap Junction-Related Neuropathologies -- Chapter 16. Postsynaptic Potentials and Synaptic Integration -- Ionotropic Receptors: Mediators of Fast Excitatory and Inhibitory Synaptic Potentials -- Metabotropic Receptors: Mediators of Slow Synaptic Potentials -- Integration of Synaptic Potentials -- Chapter 17. Information Processing in Complex Dendrites.

Strategies for Studying Complex Dendrites -- Summary: The Dendritic Tree as a Complex Information Processing System -- Chapter 18. Learning and Memory: Basic Mechanisms -- Long-Term Synaptic Potentiation and Depression -- Paradigms Have Been Developed To Study Associative and Nonassociative Learning -- Invertebrate Studies: Key Insights From Aplysia Into Basic Mechanisms of Learning -- Classical Conditioning in Vertebrates: Discrete Responses and Fear as Models of Associative Learning -- How Does a Change in Synaptic Strength Store Complex Memory? -- Summary -- Index.