Writing Reaction Mechanisms in Organic Chemistry.
Title:
Writing Reaction Mechanisms in Organic Chemistry.
Author:
Solomon, Philippa H.
ISBN:
9780080521336
Personal Author:
Edition:
2nd ed.
Physical Description:
1 online resource (487 pages)
Series:
Advanced Organic Chemistry Series
Contents:
Front Cover -- Writing Reaction Mechanisms in Organic Chemistry -- Copyright Page -- Contents -- Preface to the Second Edition -- Preface to First Edition -- Chapter 1. Introduction-Molecular Structure and Reactivity -- 1. How to Write Lewis Structures and Calculate Formal Charges -- 2. Representations of Organic Compounds -- 3. Geometry and Hybridization -- 4. Electronegativities and Dipoles -- 5. Resonance Structures -- 6. Aromaticity and Antiaromaticity -- 7. Tautomers and Equilibrium -- 8. Acidity and Basicity -- 9. Nucleophiles and Electrophiles -- Chapter 2. General Principles for Writing Reaction Mechanisms -- 1. Balancing Equations -- 2. Using Arrows to Show Moving Electrons -- 3. Mechanisms in Acidic and Basic Media -- 4. Electron-Rich Species: Bases or Nucleophiles? -- 5. Trimolecular Steps -- 6. Stability of Intermediates -- 7. Driving Forces for Reactions -- 8. Structural Relationships between Starting Materials and Products -- 9. Solvent Effects -- 10. A Last Word -- Chapter 3. Reactions of Nucleophiles and Bases -- 1. Nucleophilic Substitution -- 2. Eliminations at Saturated Carbon -- 3. Nucleophilic Addition to Carbonyl Compounds -- 4. Base-Promoted Rearrangements -- 5. Additional Mechanisms in Basic Media -- Chapter 4. Reactions Involving Acids and Other Electrophiles -- 1. Stability of Carbocations -- 2. Formation of Carbocations -- 3. The Fate of Carbocations -- 4. Rearrangement of Carbocations -- 5. Electrophilic Addition -- 6. Acid-Catalyzed Reactions of Carbonyl Compounds -- 7. Electrophilic Aromatic Substitution -- 8. Carbenes -- 9. Electrophilic Heteroatoms -- Chapter 5. Radicals and Radical Anions -- 1. Introduction -- 2. Formation of Radicals -- 3. Radical Chain Processes -- 4. Radical Inhibitors.
5. Determining the Thermodynamic Feasibility of Radical Reactions -- 6. Addition of Radicals -- 7. Fragmentation Reactions -- 8. Rearrangement of Radicals -- 9. The Srnl Reaction -- 10. The Birch Reduction -- 11. A Radical Mechanism for the Rearrangement of Some Anions -- Chapter 6. Pericyclic Reactions -- 1. Introduction -- 2. Electrocyclic Reactions -- 3. Cycloadditions -- 4. Sigmatropic Rearrangements -- 5. The Ene Reaction -- 6. A Molecular Orbital View of Pericyclic Processes -- Chapter 7. Additional Problems -- Appendix A: Lewis Structures of Common Functional Groups -- Appendix B: Symbols and Abbreviations Used in Chemical Notation -- Appendix C: Relative Acidities of Common Organic and Inorganic Substances -- Index.
Abstract:
Writing Reaction Mechanisms in Organic Chemistry, Second Edition, is an invaluable guide to charting the movements of atoms and electrons in the reactions of organic molecules. Miller and Solomon illustrate that understanding organic reactions is based on applying general principles rather than the rote memorization of unrelated processes, and, in turn, emphasize that writing mechanisms is a practical method of applying knowledge of previously encountered reactions and reaction conditions to new reactions. Students and research chemists alike will find this book useful in providing a method of organizing and synthesizing an oftentimes overwhelming quantity of information into a set of general principles and guidelines for determining and describing organic reaction mechanisms. NEW TO THIS EDITION ( Illustrated with hundreds of chemical structures, all redrawn from the first edition, with added emphasis on three-dimensional structures and stereochemical aspects of reaction mechanisms ( Extensively rewritten and reorganized to make the presentation and format more accessible to first-year organic chemistry students, as well as advanced undergraduate and graduate students ( Chapter 6 is completely revised to streamline the treatment of pericyclic reactions, while introducing the principles underlying the symmetry operations and orbital correlation diagrams ( New appendixes in this edition contain easily referenced information on Lewis structures, chemical symbols and notation, and relative acidities of common functional groups.
Local Note:
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2017. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
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