Cover -- Title Page -- Contents -- Preface -- Contributors -- 1. Pathophysiology of Seizures and Epilepsy in the Immature Brain: Cells, Synapses, and Circuits -- 2. Ion Channels, Membranes, and Molecules in Epilepsy and Neuronal Excitability -- 3. Channel Mutations in Epilepsy: A Neurodevelopmental Perspective -- 4. Metabolic and Pharmacologic Consequences of Seizures -- 5. Neuropathologic Substrates of Epilepsy -- 6. Epileptogenic Cerebral Cortical Malformations -- 7. Genetic Influences on the Risk for Epilepsy -- 8. Classification of Epilepsies in Childhood -- 9. Epidemiology of Epilepsy in Children -- 10. An Approach to the Child with Paroxysmal Phenomena with Emphasis on Nonepileptic Disorders -- 11. Evaluating the Child with Seizure -- 12. The Use of Electroencephalography in the Diagnosis of Epilepsy in Childhood -- 13. Basics of Neuroimaging in Pediatric Epilepsy -- 14. Neonatal Seizures -- 15. Severe Encephalopathic Epilepsy in Early Infancy -- 16. Severe Encephalopathic Epilepsy in Infants: Infantile Spasms (West Syndrome) -- 17. Myoclonic Epilepsies in Infancy and Early Childhood -- 18. Partial Epilepsies in Infancy -- 19. Febrile Seizures -- 20. Generalized Epilepsy with Febrile Seizures Plus (GEFS ) -- 21. Lennox-Gastaut Syndrome -- 22. Childhood Absence Epilepsies -- 23. Benign Focal Epilepsies of Childhood -- 24. The Landau-Kleffner Syndrome and Epilepsy with Continuous Spike-Waves during Sleep -- 25. Idiopathic Generalized Epilepsy of Adolescence -- 26. Progressive Myoclonus Epilepsies -- 27. Localization-Related Epilepsies: Simple Partial Seizures, Complex Partial Seizures, and Rasmussen Syndrome -- 28. Selected Disorders Associated with Epilepsy -- 29. Treatment Decisions in Childhood Seizures -- 30. Comparative Anticonvulsant Profile and Proposed Mechanisms of Action of Antiepileptic Drugs.

31. Evidence-Based Medicine Issues Related to Drug Selection -- 32. Combination Drug Therapy: Monotherapy Versus Polytherapy -- 33. Adverse Effects of Antiepileptic Drugs -- 34. Status Epilepticus and Acute Seizures -- 35. The Female Patient and Epilepsy -- 36. Teratogenic Effects of Antiepileptic Medications -- 37. Pharmacokinetic Principles of Antiepileptic Therapy in Children -- 38. Dosage Form Considerations in the Treatment of Pediatric Epilepsy -- 39. Principles of Drug Interactions: Implications for Treatment with Antiepileptic Drugs -- 40. ACTH and Steroids -- 41. Benzodiazepines -- 42. Carbamazepine and Oxcarbazepine -- 43. Ethosuximide, Methsuximide, and Trimethadione -- 44. Felbamate -- 45. Gabapentin and Pregabalin -- 46. Lamotrigine -- 47. Levetiracetam -- 48. Barbiturates and Primidone -- 49. Phenytoin and Related Drugs -- 50. Sulthiame -- 51. Tiagabine -- 52. Topiramate -- 53. Valproate -- 54. Vigabatrin -- 55. Vitamins, Herbs, and Other Alternative Therapies -- 56. Zonisamide -- 57. The Ketogenic Diet -- 58. Inflammation, Epilepsy, and Anti-Inflammatory Therapies -- 59. Antiepileptic Drugs in Development -- 60. Surgical Evaluation -- 61. Advanced Neuroimaging: PET-MRI Fusion and Diffusion Tensor Imaging -- 62. Surgical Treatment of Therapy-Resistant Epilepsy in Children -- 63. Outcome of Epilepsy Surgery in Childhood -- 64. Vagus Nerve Stimulation Therapy in Pediatric Patients: Use and Effectiveness -- 65. Economics of Pediatric Epilepsy -- 66. Quality of Life in Children with Epilepsy -- 67. Epilepsy, Cerebral Palsy, and IQ -- 68. Academic Deficits and Interventions in Pediatric Epilepsy -- 69. Cognitive Side Effects of Antiepileptic Drugs -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- X-Y -- Z.