Vascular Complications of Diabetes : Current Issues in Pathogenesis and Treatment.
Title:
Vascular Complications of Diabetes : Current Issues in Pathogenesis and Treatment.
Author:
Donnelly, Richard.
ISBN:
9780470751497
Personal Author:
Edition:
2nd ed.
Physical Description:
1 online resource (242 pages)
Contents:
VASCULAR COMPLICATIONS OF DIABETES CURRENT ISSUES IN PATHOGENESIS AND TREATMENT SECOND EDITION -- CONTENTS -- List of contributors -- Preface -- SECTION I MICRO- AND MACROVASCULAR COMPLICATIONS OF DIABETES -- Chapter 1 The public health impact of the diabetes epidemic -- Chapter 2 Risk factors -- Chapter 3 Diabetic nephropathy -- Chapter 4 Coronary heart disease and diabetes -- Chapter 5 Diabetes and cerebrovascular disease -- Chapter 6 Erectile dysfunction -- Chapter 7 Evidence-based interventions to prevent or retard vascular complications -- SECTION II DIABETIC NEUROPATHIES -- Chapter 8 Classification and clinical features of neuropathy -- Chapter 9 Pathophysiology of diabetic neuropathy -- Chapter 10 Epidemiology and natural history of DPN -- Chapter 11 Detection/Screening/Assessment -- Chapter 12 Foot ulceration and Charcot arthropathy -- Chapter 13 Treatments options -- Chapter 14 Management guidelines for diabetic peripheral neuropathy and foot ulceration -- SECTION III DIABETIC RETINOPATHY AND ASSOCIATED OPHTHALMIC DISORDERS -- Chapter 15 Diabetic retinopathy: epidemiology and risk factors -- Chapter 16 Classification and diagnosis of diabetic retinopathy -- Chapter 17 Diabetic maculopathy -- Chapter 18 Proliferative diabetic retinopathy -- Chapter 19 Non-retinal diabetic ocular complications -- SECTION IV MECHANISMS OF HYPERGLYCAEMIA INDUCED VASCULAR DYSFUNCTION -- Chapter 20 Pathophysiology and potential targets for therapeutic intervention -- Chapter 21 Protein kinase C -- Chapter 22 Protein kinase C activation and vascular permeability -- Chapter 23 Role of protein kinase Cactivation in cardiovascular and renal complications of diabetes -- Chapter 24 Experimental pharmacology using isoform-selective protein kinase Cinhibitors -- Chapter 25 Clinical trials with ruboxistaurin -- Index.
Abstract:
Diabetes has reached epidemic proportions, and the cardiovascular complications of diabetes are life-threatening and disabling. This book is unique in providing a simple explanation of the biochemical role of PKC in diabetes complications, which allows clinicians to understand why PKC inhibitors (in development) are an exciting prospect for future treatment to slow progression of eye & foot complications. New features of this Second Edition include: Updated throughout to reflect the impact of recent major clinical trials on current clinical practice Includes a major new section on diabetic neuropathy Revised section on diabetic retinopathy Each chapter is short and succinct, focusing on 'best practice'. There are key learning points at the end of each chapter, with numerous helpful tables, figures and clinical images.
Local Note:
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2017. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
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