CONTENTS -- Part 1. General Principles -- 1. OVERVIEW -- INTRODUCTION -- RATIONALE FOR NEURO-ONCOLOGY -- CLASSIFICATION OF NEURO-ONCOLOGIC DISORDERS -- APPROACH TO THE PATIENT -- EVALUATING THE PATIENT -- REFERENCES -- 2. PATHOPHYSIOLOGY OF NERVOUS SYSTEM METASTASES -- INTRODUCTION -- PATHOPHYSIOLOGY OF THE METASTATIC PROCESS -- CLINICAL CONSIDERATIONS RELEVANT TO NERVOUS SYSTEM METASTASIS -- PATHOPHYSIOLOGIC FACTORS RELEVANT TO SPREAD AND GROWTH OF CANCER TO SPECIFIC NEURAL STRUCTURES -- REFERENCES -- 3. BLOOD-NERVOUS SYSTEM BARRIER DYSFUNCTION: PATHOPHYSIOLOGY AND TREATMENT -- INTRODUCTION -- ANATOMY AND PHYSIOLOGY -- DISRUPTION OF BLOOD-CENTRAL NERVOUS SYSTEM BARRIERS -- CONSEQUENCES OF BLOOD-BRAIN BARRIER DISRUPTION: INCREASED INTRACRANIAL PRESSURE, PLATEAU WAVES, AND CEREBRAL HERNIATION -- TRANSPORT OF CHEMOTHERAPEUTIC DRUGS ACROSS THE BLOOD-BRAIN BARRIER -- RESTORATION OF BLOOD-CENTRAL NERVOUS SYSTEM BARRIERS -- REFERENCES -- 4. SUPPORTIVE CARE AND ITS COMPLICATIONS -- INTRODUCTION -- EDEMA/CORTICOSTEROIDS -- SEIZURES/ANTICONVULSANTS -- VENOUS THROMBOSIS/ANTICOAGULANTS -- PAIN/ANALGESIA -- PSYCHOLOGICAL DISTRESS/PSYCHOTROPIC AGENTS -- FATIGUE -- NAUSEA, VOMITING/ANTIEMETIC AGENTS -- INFECTION/ANTIBIOTICS -- INTENSIVE CARE/COMMON AGENTS -- REFERENCES -- Part 2. Metastases -- 5. INTRACRANIAL METASTASES -- GENERAL PRINCIPLES -- BRAIN METASTASES (PARENCHYMAL) -- SPECIFIC TUMORS -- LESS COMMON SITES OF INTRACRANIAL METASTASES -- REFERENCES -- 6. SPINAL METASTASES -- INTRODUCTION -- EPIDURAL METASTASES -- INTRADURAL AND INTRAMEDULLARY METASTASES -- REFERENCES -- 7. LEPTOMENINGEAL METASTASES -- INTRODUCTION -- FREQUENCY -- PATHOPHYSIOLOGY OF SIGNS AND SYMPTOMS -- CLINICAL FINDINGS -- LABORATORY TESTS -- DIFFERENTIAL DIAGNOSIS -- TREATMENT -- PROGNOSIS -- REFERENCES -- 8. CANCER INVOLVING CRANIAL AND PERIPHERAL NERVES AND MUSCLES -- INTRODUCTION.

FREQUENCY -- CRANIAL NERVES -- SPINAL ROOTS -- NERVE PLEXUSES -- PERIPHERAL NERVES -- MUSCLES -- REFERENCES -- Part 3. Nonmetastatic Complications of Cancer -- 9. VASCULAR DISORDERS -- INTRODUCTION -- FREQUENCY -- PATHOPHYSIOLOGY OF CEREBROVASCULAR DISEASE -- CENTRAL NERVOUS SYSTEM HEMORRHAGE -- CENTRAL NERVOUS SYSTEM INFARCTION -- VENOUS OCCLUSIONS -- OTHER DISORDERS -- APPROACH TO THE PATIENT -- REFERENCES -- 10. CENTRAL NERVOUS SYSTEM INFECTIONS -- INTRODUCTION -- PATHOPHYSIOLOGY OF CENTRAL NERVOUS SYSTEM INFECTION -- CLINICAL FINDINGS -- APPROACH TO THE PATIENT -- SPECIFIC ORGANISMS CAUSING CENTRAL NERVOUS SYSTEM INFECTION IN PATIENTS WITH CANCER -- REFERENCES -- 11. DELIRIUM AND METABOLIC AND NUTRITIONAL COMPLICATIONS OF CANCER -- INTRODUCTION -- DELIRIUM ASSOCIATED WITH CANCER -- METABOLIC BRAIN DISEASE IN PATIENTS WITH CANCER -- SPECIFIC METABOLIC CAUSES OF DELIRIUM -- NUTRITIONAL DISORDERS ASSOCIATED WITH CANCER -- REFERENCES -- 12. SIDE EFFECTS OF CHEMOTHERAPY -- INTRODUCTION -- CLINICAL FINDINGS AND DIAGNOSIS -- SPECIFIC AGENTS -- REFERENCES -- 13. SIDE EFFECTS OF RADIATION THERAPY -- INTRODUCTION -- BIOLOGY OF RADIATION DAMAGE -- DIAGNOSIS OF RADIATION-INDUCED NEUROTOXICITY -- TREATMENT -- REFERENCES -- 14. NEUROTOXICITY OF SURGICAL AND DIAGNOSTIC PROCEDURES -- INTRODUCTION -- DISORDERS RESULTING FROM ANESTHESIA -- SURGERY -- DIAGNOSTIC PROCEDURES CAUSING NEUROTOXICITY -- REFERENCES -- 15. PARANEOPLASTIC SYNDROMES -- INTRODUCTION -- GENERAL CONSIDERATIONS -- SPECIFIC SYNDROMES -- REFERENCES -- INDEX -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- X -- Z.