The Central Mississippi Valley, defined as the region along the Mississippi River from where the Ohio River joins in the north to its confluence with the Arkansas River in the south, lies between the two most important archaeological areas of the Southeast: American Bottom/Cahokia and the Lower Yazoo Basin. The valley has been influenced by these major centers and has a complex history of its own. Contributions from experts throughout the region present current, if sometimes conflicting, views of the regional cultural sequences supported by data from recent surveys and excavations, as well as radiocarbon and chronometric determinations. By examining this new information and reevaluating earlier interpretations of local archaeological sequences, this volume provides a comprehensive overview of the valley and defines future research goals.