Essentials of Biostatistics for Physicians, Nurses, and Clinicians.
Title:
Essentials of Biostatistics for Physicians, Nurses, and Clinicians.
Author:
Chernick, Michael R.
ISBN:
9781118071939
Personal Author:
Edition:
1st ed.
Physical Description:
1 online resource (226 pages)
Contents:
The Essentials of Biostatistics for Physicians, Nurses, and Clinicians -- Contents -- Preface -- CHAPTER 1: The What, Why, and How of Biostatistics in Medical Research -- 1.1 DEFINITION OF STATISTICS AND BIOSTATISTICS -- 1.2 WHY STUDY STATISTICS? -- 1.3 THE MEDICAL LITERATURE -- 1.4 MEDICAL RESEARCH STUDIES -- 1.4.1 Cross-Sectional Studies Including Surveys -- 1.4.2 Retrospective Studies -- 1.4.3 Prospective Studies Other Than Clinical Trials -- 1.4.4 Controlled Clinical Trials -- 1.4.5 Conclusions -- 1.5 EXERCISES -- CHAPTER 2: Sampling from Populations -- 2.1 DEFINITIONS OF POPULATIONS AND SAMPLES -- 2.2 SIMPLE RANDOM SAMPLING -- 2.3 SELECTING SIMPLE RANDOM SAMPLES -- 2.4 OTHER SAMPLING METHODS -- 2.5 GENERATING BOOTSTRAP SAMPLES -- 2.6 EXERCISES -- CHAPTER 3: Graphics and Summary Statistics -- 3.1 CONTINUOUS AND DISCRETE DATA -- 3.2 CATEGORICAL DATA -- 3.3 FREQUENCY HISTOGRAMS -- 3.4 STEM-AND-LEAF DIAGRAMS -- 3.5 BOX PLOTS -- 3.6 BAR AND PIE CHARTS -- 3.7 MEASURES OF THE CENTER OF A DISTRIBUTION -- 3.8 MEASURES OF DISPERSION -- 3.9 EXERCISES -- CHAPTER 4: Normal Distribution and Related Properties -- 4.1 AVERAGES AND THE CENTRAL LIMIT THEOREM -- 4.2 STANDARD ERROR OF THE MEAN -- 4.3 STUDENT'S T-DISTRIBUTION -- 4.4 EXERCISES -- CHAPTER 5: Estimating Means and Proportions -- 5.1 THE BINOMIAL AND POISSON DISTRIBUTIONS -- 5.2 POINT ESTIMATES -- 5.3 CONFIDENCE INTERVALS -- 5.4 SAMPLE SIZE DETERMINATION -- 5.5 BOOTSTRAP PRINCIPLE AND BOOTSTRAP CONFIDENCE INTERVALS -- 5.6 EXERCISES -- CHAPTER 6: Hypothesis Testing -- 6.1 TYPE I AND TYPE II ERRORS -- 6.2 ONE-TAILED AND TWO-TAILED TESTS -- 6.3 P-VALUES -- 6.4 COMPARING MEANS FROM TWO INDEPENDENT SAMPLES: TWO-SAMPLE T-TEST -- 6.5 PAIRED T-TEST -- 6.6 TESTING A SINGLE BINOMIAL PROPORTION -- 6.7 RELATIONSHIP BETWEEN CONFIDENCE INTERVALS AND HYPOTHESIS TESTS -- 6.8 SAMPLE SIZE DETERMINATION.
6.9 BOOTSTRAP TESTS -- 6.10 MEDICAL DIAGNOSIS: SENSITIVITY AND SPECIFICITY -- 6.11 SPECIAL TESTS IN CLINICAL RESEARCH -- 6.11.1 Superiority Tests -- 6.11.2 Equivalence and Bioequivalence -- 6.11.3 Noninferiority Tests -- 6.12 REPEATED MEASURES ANALYSIS OF VARIANCE AND LONGITUDINAL DATA ANALYSIS -- 6.13 META-ANALYSIS -- 6.14 EXERCISES -- CHAPTER 7: Correlation, Regression, and Logistic Regression -- 7.1 RELATIONSHIP BETWEEN TWO VARIABLES AND THE SCATTER PLOT -- 7.2 PEARSON'S CORRELATION -- 7.3 SIMPLE LINEAR REGRESSION AND LEAST SQUARES ESTIMATION -- 7.4 SENSITIVITY TO OUTLIERS AND ROBUST REGRESSION -- 7.5 MULTIPLE REGRESSION -- 7.6 LOGISTIC REGRESSION -- 7.7 EXERCISES -- CHAPTER 8: Contingency Tables -- 8.1 2 × 2 TABLES AND CHI-SQUARE -- 8.2 SIMPSON'S PARADOX IN THE 2 × 2 TABLE -- 8.3 THE GENERAL R × C TABLE -- 8.4 FISHER'S EXACT TEST -- 8.5 CORRELATED PROPORTIONS AND MCNEMAR'S TEST -- 8.6 RELATIVE RISK AND ODDS RATIO -- 8.7 EXERCISES -- CHAPTER 9: Nonparametric Methods -- 9.1 RANKING DATA -- 9.2 WILCOXON RANK-SUM TEST -- 9.3 SIGN TEST -- 9.4 SPEARMAN'S RANK-ORDER CORRELATION COEFFICIENT -- 9.5 INSENSITIVITY OF RANK TESTS TO OUTLIERS -- 9.6 EXERCISES -- CHAPTER 10: Survival Analysis -- 10.1 TIME-TO-EVENT DATA AND RIGHT CENSORING -- 10.2 LIFE TABLES -- 10.3 KAPLAN -MEIER CURVES -- 10.3.1 The Kaplan-Meier Curve: A Nonparametric Estimate of Survival -- 10.3.2 Confidence Intervals for the Kaplan-Meier Estimate -- 10.3.3 The Logrank and Chi-Square Tests: Comparing Two or More Survival Curves -- 10.4 PARAMETRIC SURVIVAL CURVES -- 10.4.1 Negative Exponential Survival Distributions -- 10.4.2 Weibull Family of Survival Distributions -- 10.5 COX PROPORTIONAL HAZARD MODELS -- 10.6 CURE RATE MODELS -- 10.7 EXERCISES -- Solutions to Selected Exercises -- APPENDIX: Statistical Tables -- References -- Author Index -- Subject Index.
Abstract:
A fundamental and straightforward guide to using and understanding statistical concepts in medical research Designed specifically for healthcare practitioners who need to understand basic biostatistics but do not have much time to spare, The Essentials of Biostatistics for Physicians, Nurses and Clinicians presents important statistical methods used in today's biomedical research and provides insight on their appropriate application. Rather than provide detailed mathematics for each of these methods, the book emphasizes what healthcare practitioners need to know to interpret and incorporate the latest biomedical research into their practices. The author draws from his own experience developing and teaching biostatistics courses for physicians and nurses, offering a presentation that is non-technical and accessible. The book begins with a basic introduction to the relationship between biostatistics and medical research, asking the question "why study statistics?," while also exploring the significance of statisitcal methods in medical literature and clinical trials research. Subsequent chapters explore key topics, including: Correlation, regression, and logistic regression Diagnostics Estimating means and proportions Normal distribution and the central limit theorem Sampling from populations Contingency tables Meta-analysis Nonparametric methods Survival analysis Throughout the book, statistical methods that are often utilized in biomedical research are outlined, including repeated measures analysis of variance, hazard ratios, contingency tables, log rank tests, bioequivalence, cross-over designs, selection bias, and group sequential methods. Exercise sets at the end of each chapter allow readers to test their comprehension of the presented concepts and techniques. The Essentials of Biostatistics for Physicians, Nurses, and Clinicians is
an excellent reference for doctors, nurses, and other practicing clinicians in the fields of medicine, public health, pharmacy, and the life sciences who need to understand and apply statistical methods in their everyday work. It also serves as a suitable supplement for courses on biostatistics at the upper-undergraduate and graduate levels.
Local Note:
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2017. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
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