Advances in Chemical Physics, Single Molecule Biophysics : Experiments and Theory.
Title:
Advances in Chemical Physics, Single Molecule Biophysics : Experiments and Theory.
Author:
Komatsuzaki, Tamiki.
ISBN:
9781118131404
Personal Author:
Edition:
1st ed.
Physical Description:
1 online resource (520 pages)
Series:
Advances in Chemical Physics ; v.314
Advances in Chemical Physics
Contents:
Single-Molecule Biophysics: Experiment and Theory -- CONTENTS -- Preface -- Part One: Developments on Single-Molecule Experiments -- Staring at a Protein: Ensemble and Single-Molecule Investigations on Protein-Folding Dynamics -- Single-Molecule FRET of Protein-Folding Dynamics -- Quantitative Analysis of Single-Molecule FRET Signals and its Application to Telomere DNA -- Force to Unbind Ligand-Receptor Complexes and the Internal Rigidity of Globular Proteins Probed by Single-Molecule Force Spectroscopy -- Recent Advances in Single-Molecule Biophysics with the Use of Atomic Force Microscopy -- Dynamical Single-Molecule Observations of Membrane Protein Using High-Energy Probes -- Single-Molecular Gating Dynamics for the KcsA Potassium Channel -- Static and Dynamic Disorder in IN VITRO Reconstituted Receptor-Adaptor Interaction -- Part Two: Developments on Single-Molecule Theories and Analyses -- Change-Point Localization and Wavelet Spectral Analysis of Single-Molecule Time Series -- Theory of Single-Molecule FRET Efficiency Histograms -- Multidimensional Energy Landscapes in Single-Molecule Biophysics -- Generalized Michaelis-Menten Equation for Conformation Modulated Monomeric Enzymes -- Making it Possible: Constructing a Reliable Mechanism from a Finite Trajectory -- Free Energy Landscapes of Proteins: Insights from Mechanical Probes -- Mechanochemical Coupling Revealed by the Fluctuation Analysis of Different Biomolecular Motors -- Author Index -- Subject Index -- Colour Plates.
Abstract:
Discover the experimental and theoretical developments in optical single-molecule spectroscopy that are changing the ways we think about molecules and atoms The Advances in Chemical Physics series provides the chemical physics field with a forum for critical, authoritative evaluations of advances in every area of the discipline. This latest volume explores the advent of optical single-molecule spectroscopy, and how atomic force microscopy has empowered novel experiments on individual biomolecules, opening up new frontiers in molecular and cell biology and leading to new theoretical approaches and insights. Organized into two parts-one experimental, the other theoretical-this volume explores advances across the field of single-molecule biophysics, presenting new perspectives on the theoretical properties of atoms and molecules. Single-molecule experiments have provided fresh perspectives on questions such as how proteins fold to specific conformations from highly heterogeneous structures, how signal transductions take place on the molecular level, and how proteins behave in membranes and living cells.This volume is designed to further contribute to the rapid development of single-molecule biophysics research. Filled with cutting-edge research reported in a cohesive manner not found elsewhere in the literature, each volume of the Advances in Chemical Physics series serves as the perfect supplement to any advanced graduate class devoted to the study of chemical physics.
Local Note:
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2017. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
Genre:
Electronic Access:
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