Translational Neuroscience : A Guide to a Successful Program -- Contents -- Contributors -- Preface -- Acknowledgments -- 1 A Brief History of Translational Neuroscience -- Some recent history -- Funding translational research -- Lack of funding -- Making NIH funding more equitable and efficient -- How much funding is needed? -- Medical research funding in Europe -- References -- 2 Mentoring in Translational Neuroscience -- T1 blocks -- T2 blocks -- References -- 3 Core Facilities for Translational Neuroscience -- Designing translational neuroscience core facilities -- Preattentional measure-the P50 potential -- Attentional measures-psychomotor vigilance -- Frontal lobe blood flow measures -- References -- 4 Translational Studies Using TMS -- Overview -- Introduction -- Development of a sham stimulation technique for humans -- PET-guided TMS studies of tinnitus perception -- TMS investigations of decision-making in tobacco addiction -- TMS investigations in rodents -- Conclusion -- References -- 5 Translational Studies in Drug Abuse -- Background and significance -- Behavioral Core Facility -- Voltage-sensitive dye imaging -- Intravenous drug self-administration -- References -- 6 Electrophysiology in Translational Neuroscience -- In vivo and in vitro animal models -- Modafinil -- Patch clamp recordings -- Gamma band activity -- Population responses -- Preconscious awareness -- Magnetoencephalography, the Cadillac of human electrophysiology -- References -- 7 Translational Research on Spinal Cord Injury -- Electrophysiological approach: H-reflex frequency-dependent depression -- Biomechanical approach: windup of the stretch reflex -- Interventions: passive exercise -- Interventions: pharmacology (L-Dopa, Modafinil) -- Conclusions -- References -- 8 Translational Research in Neonatology -- Introduction -- The need for neonatal research.

The building blocks: basic research -- Pups to babies and back again: T1 Research -- No problem can be solved unless it is first identified -- From the bedside to the community: T2 research -- The role of comparative effectiveness research -- Barriers and rewards in translational research in neonatology -- Opportunities for translational research in neonatology -- Conclusion -- References -- 9 Telemedicine in Translational Neuroscience -- History of telemedicine -- Enabling access to care -- Telemedicine Core Facility -- Neonatal intensive care -- Emergency departments -- Conclusion -- References -- 10 Implications for the Future -- Fragmented infrastructure -- Incompatible databases -- The benefits of translational research -- The reshaping of basic science departments -- References -- Index -- Color plates appear between pages 96 and 97.