APPLICATIONS OF IONCHROMATOGRAPHYFOR PHARMACEUTICALAND BIOLOGICALPRODUCTS -- CONTENTS -- CONTRIBUTORS -- PREFACE -- PART I PRINCIPLES, MECHANISM,AND INSTRUMENTATION -- 1 ION CHROMATOGRAPHY-PRINCIPLES AND APPLICATIONS -- 2 RETENTION PROCESSES IN ION-EXCLUSIONCHROMATOGRAPHY: A NEW PERSPECTIVE -- 3 PULSED ELECTROCHEMICAL DETECTION IN IONCHROMATOGRAPHY -- 4 SUPPRESSOR DESIGN AND DETECTION FOR IONCHROMATOGRAPHY -- 5 MODELLING AND OPTIMIZATION OF IONCHROMATOGRAPHIC SEPARATIONS OF PHARMACEUTICALLYRELEVANT ORGANIC IONS -- PART II PHARMACEUTICAL APPLICATIONS -- 6 ION CHROMATOGRAPHY IN PHARMACEUTICAL DRUGANALYSIS -- 7 ANALYSIS FOR IMPURITIES BY IONCHROMATOGRAPHY -- 8 ION CHROMATOGRAPHY ANALYSIS OF AMINOGLYCOSIDEANTIBIOTICS -- 9 USE OF CATION-EXCHANGE ION CHROMATOGRAPHYIN THE ANALYSIS OF PHARMACEUTICALS -- 10 COMPREHENSIVE APPROACHES FOR MEASUREMENTOF ACTIVE PHARMACEUTICAL INGREDIENTS, COUNTER-IONS,AND EXCIPIENTS USING HPLC WITH CHARGED AEROSOLDETECTION -- 11 HIGH PERFORMANCE ION CHROMATOGRAPHIC ANALYSISOF CHOLINERGIC COMPOUNDS: CARBACHOLAND BETHANECHOL, AND ASSOCIATED DEGRADATIONPRODUCTS -- 12 ION CHROMATOGRAPHIC ANALYSIS OF PHARMACEUTICALSFOR AUTHENTICITY AND ADULTERATION -- 13 ION CHROMATOGRAPHY OF DRUG PRODUCT COUNTER-IONSAND OTHER IONS IN DRUG PRODUCTS -- 14 SAMPLE PREPARATION TECHNIQUES IN IONCHROMATOGRAPHY FOR PHARMACEUTICALAPPLICATIONS -- 15 VALIDATION OF ION CHROMATOGRAPHIC METHODS -- 16 PHARMACOPEIAL APPLICATIONS OF IONCHROMATOGRAPHY -- PART III BIOTECHNOLOGY APPLICATIONS -- 17 GLYCAN ANALYSIS BY HIGH PERFORMANCE ANIONEXCHANGE CHROMATOGRAPHY WITH PULSEDAMPEROMETRIC DETECTION -- 18 MONOSACCHARIDE ANALYSIS OF GLYCOPROTEINSBY HIGH-PERFORMANCE ANION-EXCHANGECHROMATOGRAPHY WITH PULSED AMPEROMETRICDETECTION -- 19 TWO-DIMENSIONAL ION CHROMATOGRAPHY FORSIMULTANEOUS DETERMINATION OF AMINO ACIDS ANDCARBOHYDRATES.

20 MONITORING PROTEIN N-GLYCOSYLATION CONSISTENCYUSING HPAEC-PAD -- 21 OLIGOSACCHARIDE ANALYSIS BY HIGH-PERFORMANCEANION-EXCHANGE CHROMATOGRAPHY HYPHENATEDTO INTEGRATED PULSED AMPEROMETRIC DETECTIONAND ON-LINE ION-TRAP MASS SPECTROMETRY -- PART IV VACCINE APPLICATIONS -- 22 APPLICATIONS OF ION CHROMATOGRAPHY IN BIOLOGICALPRODUCT ANALYSES -- 23 HIGH PERFORMANCE ANION-EXCHANGE CHROMATOGRAPHYWITH PULSED AMPEROMETRIC DETECTION (HPAEC-PAD)ANALYSIS OF GBS GLYCOCONJUGATE VACCINES:FROM FERMENTATION TO FINAL PRODUCT -- 24 STABILITY STUDIES AND CHARACTERIZATION OFMENINGOCOCCAL A, C, Y, AND W135 GLYCOCONJUGATEVACCINE -- PART V APPENDICES -- Appendix 1 DISSOCIATION CONSTANTS (pKa) OF ORGANICACIDS (AT 20◦C) -- Appendix 2 DISSOCIATION CONSTANTS (pKa) OF COMMONSUGARS AND ALCOHOLS -- INDEX.