Biomedical Sciences: Essential Laboratory Medicine -- Contents -- List of Contributors -- Preface -- Chapter 1: Anatomy and physiology of major organ systems -- 1.1 The skeletal system -- 1.2 The digestive system -- 1.3 The cardiovascular system -- 1.4 The urinary system -- 1.5 Respiratory system -- 1.6 The nervous system -- 1.7 The endocrine system -- Bibliography -- Chapter 2: Pathophysiology -- 2.1 Pathophysiology: a definition -- 2.2 Introduction to epidemiology -- 2.3 Introduction to pharmacology -- 2.4 Gastroenterology -- 2.5 Liver, biliary tract and pancreatic disease -- 2.6 Rheumatology -- 2.7 Urinary tract disease -- 2.8 Cardiovascular disease -- 2.9 Respiratory disease -- 2.10 Endocrine disease -- Bibliography -- Chapter 3: Clinical cell biology and genetics -- 3.1 The cell -- 3.2 Genetics -- 3.3 Human genetic disorders -- 3.4 Important techniques in molecular cell biology -- Bibliography -- Chapter 4: Cellular pathology -- Part I: Principles of cellular pathology -- 4.1 Structure and function of normal cells, tissues and organs -- 4.2 Tissues and organs -- 4.3 Cellular responses to injury -- 4.4 Tissue responses to injury: acute inflammation -- 4.5 Tissue responses to injury: chronic inflammation -- 4.6 Healing and repair -- 4.7 Hyperplasia and hypertrophy -- 4.8 Atherosclerosis -- 4.9 Thrombosis and embolism -- 4.10 Ischaemia and infarction -- 4.11 Amyloid and amyloidosis -- 4.12 Infections of histological importance -- 4.13 Metaplasia, dysplasia and carcinoma in situ -- 4.14 Neoplasia -- Part II: Clinical application and laboratory techniques -- 4.15 Sampling modalities -- 4.16 Fixation -- 4.17 Specimen dissection -- 4.18 Processing and embedding -- 4.19 Microtomy -- 4.20 Standard staining methods and procedures -- 4.21 Frozen section -- 4.22 Immunohistochemistry -- 4.23 Cytopathology -- 4.24 Electron microscopy.

4.25 In situ hybridization -- Bibliography -- Chapter 5: Clinical chemistry -- Introduction -- Part I: Analytical methods -- 5.1 Sample collection -- 5.2 Analytical methods in clinical chemistry laboratories -- 5.3 Summary: common clinical tests for sample analytes -- Part II: Clinical assessments -- 5.4 Urea and electrolytes (U and Es) -- 5.5 Metabolism and gastrointestinal markers -- 5.6 Renal function tests -- 5.7 Liver function tests -- 5.8 Heart disease and lipid disorder tests -- 5.9 Pancreatic function tests -- 5.10 Bone disease assessment -- 5.11 Endocrinological assessments -- 5.12 Pregnancy tests and pregnancy clinical chemistry -- 5.13 Therapeutic drug monitoring and toxicology -- 5.14 Clinical chemistry at the extremes of age -- 5.15 Cancer biomarkers -- Bibliography -- Chapter 6 Medical microbiology -- Introduction -- 6.1 Overview of microorganisms -- 6.2 Laboratory investigation of infection -- 6.3 Bacteria -- 6.4 Fungi -- 6.5 Parasitology --- protozoa and helminths -- 6.6 Viruses -- 6.7 Prions -- 6.8 Infections in the immunocompromised patient -- 6.9 Healthcare associated infections -- 6.10 Antimicrobial agents -- 6.11 Vaccines -- 6.12 Conclusion -- Bibliography -- Chapter 7 Clinical immunology -- Part I: The fundamentals of immunology -- 7.1 Overview of the immune system -- 7.2 Overview of the immune response -- 7.3 MHC genotyping, autoimmunity and susceptibility to disease -- 7.4 Physical age and immunocompetency -- Part II: Laboratory investigations and immune assessments -- 7.5 Inflammation and chronic infection -- 7.6 Autoimmune diseases -- 7.7 Transplant rejection -- 7.8 Hypersensitivities -- 7.9 Immune deficiency -- Bibliography -- Chapter 8 Haematology and transfusion science -- 8.1 Introduction and components of blood -- 8.2 Routine laboratory blood tests -- 8.3 Haemopoiesis.

8.4 Red blood cell structure, disorders and metabolism -- 8.5 Haemoglobin -- 8.6 Anaemia -- 8.7 Benign white blood cell disorders -- 8.8 Haemostasis -- 8.9 Coagulation disorders -- 8.10 Myeloproliferative disorders -- 8.11 Haematological malignancies -- 8.12 Complement -- 8.13 Blood transfusion -- 8.14 Blood products -- 8.15 Haemopoetic stem cell transplantation -- Bibliography -- Chapter 9 Professional practice and biomedical science -- 9.1 What is a biomedical scientist? -- 9.2 The IBMS -- 9.3 Professional practice and the role of the HPC -- 9.4 Standards of proficiency --- biomedical scientists -- 9.5 Expectations of a health professional -- 9.6 Professional relationships -- 9.7 The skills required for the application of practice -- 9.8 Knowledge, understanding and skills -- 9.9 Standards of conduct, performance and ethics -- 9.10 CPD -- 9.11 Critical reflection -- 9.12 IBMS CPD scheme -- 9.13 The professional biomedical scientist as an agent for change in the wider healthcare setting -- Appendix -- Index.