Front Cover -- Gas Chromatography -- Copyright -- Contents -- Contributors -- Chapter 1 - Milestones in the Development of Gas Chromatography -- 1.1. INTRODUCTION -- 1.2. THE INVENTION OF GAS CHROMATOGRAPHY -- 1.3. EARLY INSTRUMENTATION -- 1.4. EARLY COLUMN DEVELOPMENTS -- 1.5. INTERFACING GLASS CAPILLARY COLUMNS TO INJECTORS AND DETECTORS -- 1.6. THE HINDELANG CONFERENCES AND THE FUSED-SILICA COLUMN -- 1.7. INCREASING SOPHISTICATION OF INSTRUMENTATION -- 1.8. DECLINE IN THE EXPERTISE OF THE AVERAGE GAS CHROMATOGRAPHER -- References -- Chapter 2 - Theory of Gas Chromatography -- 2.1. INTRODUCTION -- 2.2. NOMENCLATURE AND OTHER CONVENTIONS -- 2.3. GENERAL DEFINITIONS -- 2.4. SOLUTE-COLUMN INTERACTION -- 2.5. PROPERTIES OF AN IDEAL GAS -- 2.6. FLOW OF IDEAL GAS IN OPEN CIRCULAR TUBES -- 2.7. MIGRATION AND ELUTION PARAMETERS OF THE SOLUTES -- 2.8. PEAK SPACING AND REVERSAL OF PEAK ORDER -- 2.9. PEAK WIDTH -- 2.10. OPTIMIZATION -- References -- Chapter 3 - Column Technology: Open Tubular Columns -- 3.1. INTRODUCTION -- 3.2. OVERVIEW OF THE FUSED SILICA DRAWING PROCESS -- 3.3. THE PREFORM - RAW MATERIAL -- 3.4. SURFACE CHEMISTRY -- 3.5. DRAWING OF THE CAPILLARY FROM THE PREFORM -- 3.6. PROTECTIVE COATING -- 3.7. ALTERNATIVE PROTECTIVE COATINGS -- 3.8. CLEANROOM ENVIRONMENT -- 3.9. QUALITY MONITORING -- 3.10. OBSERVATIONS ON HANDLING OF FUSED-SILICA CAPILLARY TUBING -- 3.11. COLUMN TECHNOLOGY - COATING THE STATIONARY PHASE -- 3.12. STATIONARY PHASES -- 3.13. COATING TECHNIQUES -- 3.14. COLUMN TECHNOLOGY - QUALITY EVALUATION -- 3.15. COLUMN TECHNOLOGY - SUMMARY -- References -- Chapter 4 - Packed Columns for Gas-Liquid and Gas-Solid Chromatography -- 4.1. INTRODUCTION -- 4.2. GAS-LIQUID CHROMATOGRAPHY -- 4.3. GAS-SOLID CHROMATOGRAPHY -- References -- Chapter 5 - Gas-Solid Chromatography (PLOT Columns) -- 5.1. ALUMINA ADSORBENTS -- 5.2. MOLECULAR SIEVES.

5.3. POROUS POLYMERS -- 5.4. CARBON ADSORBENTS -- 5.5. OTHER ADSORBENTS -- References -- Chapter 6 - Classification and Selection of Open-Tubular Columns for Analytical Separations -- 6.1. INTRODUCTION -- 6.2. STATIONARY-PHASE CLASSIFICATION -- 6.3. POROUS-LAYER OPEN-TUBULAR COLUMNS -- 6.4. TEMPERATURE-PROGRAMMED SEPARATIONS -- 6.5. STATIONARY-PHASE SELECTIVITY TUNING -- References -- Chapter 7 - Multidimensional and Comprehensive Gas Chromatography -- 7.1. INTRODUCTION -- 7.2. A GRAPHICAL REPRESENTATION OF 2D GC SEPARATIONS -- 7.3. BACKFLUSHING 2D GC -- 7.4. HEARTCUTTING 2D GC -- 7.5. COMPREHENSIVE 2D GC -- 7.6. CONCLUSIONS -- References -- Chapter 8 - Sample Introduction Methods -- 8.1. INTRODUCTION -- 8.2. CHOOSING A SAMPLE INTRODUCTION SYSTEM -- 8.3. SUPPORTING DEVICES -- 8.4. THE COLD ON-COLUMN INJECTOR -- 8.5. THE FLASH VAPORIZATION INJECTOR -- 8.6. THE SPLIT/SPLITLESS INJECTOR -- 8.7. THE PROGRAMMABLE TEMPERATURE VAPORIZING (PTV) INJECTOR -- 8.8. THE GAS SAMPLING VALVE -- 8.9. THE LIQUID SAMPLING VALVE -- References -- Chapter 9 - Headspace-Gas Chromatography -- 9.1. INTRODUCTION AND HISTORY -- 9.2. FUNDAMENTALS OF HEADSPACE EXTRACTION -- 9.3. INSTRUMENTATION AND PRACTICE -- 9.4. METHOD DEVELOPMENT CONSIDERATIONS -- 9.5. CONCLUSIONS -- References -- Chapter 10 - Thermal Desorption for Gas Chromatography -- 10.1. GENERAL INTRODUCTION TO THERMAL DESORPTION -- 10.2. BRIEF HISTORY OF THERMAL DESORPTION - ESSENTIAL FUNCTIONS AND PERFORMANCE CHARACTERISTICS -- 10.3. THE EVOLUTION OF TD TECHNOLOGY -- 10.4. SAMPLING OPTIONS AND THE ROLE OF THERMAL DESORPTION AS A FRONTEND TECHNOLOGY FOR GC -- 10.5. METHOD DEVELOPMENT AND OPTIMIZATION -- 10.6. CALIBRATION AND VALIDATION -- 10.7. AN INTRODUCTION TO THERMAL DESORPTION APPLICATIONS -- 10.8. AIR MONITORING -- 10.9. CHEMICAL EMISSIONS FROM EVERYDAY PRODUCTS TO INDOOR AIR.

10.10. TOXIC CHEMICAL AGENTS AND CIVIL DEFENSE -- 10.11. TD-GC(MS) ANALYSIS OF RESIDUAL VOLATILES -- 10.12. FLAVOR, FRAGRANCE, AND ODOR PROFILING -- 10.13. FORENSIC APPLICATIONS -- 10.14. MONITORING MANUFACTURING AND OTHER INDUSTRIAL CHEMICAL PROCESSES -- 10.15. NEW GC-RELATED TECHNOLOGY DEVELOPMENTS WHICH BENEFIT THERMAL DESORPTION -- 10.16. CONCLUDING REMARKS -- References -- Chapter 11 - Pyrolysis Gas Chromatography -- 11.1. THERMAL SAMPLING GC -- 11.2. CHEMICAL THEORY -- 11.3. INSTRUMENTATION -- 11.4. APPLICATIONS -- References -- Chapter 12 - Detectors -- 12.1. INTRODUCTION -- 12.2. THERMAL CONDUCTIVITY DETECTOR -- 12.3. FLAME IONIZATION DETECTOR -- 12.4. ELECTRON-CAPTURE DETECTOR -- 12.5. ALKALI BEAD DETECTOR -- 12.6. FLAME PHOTOMETRIC DETECTOR -- 12.7. PHOTOIONIZATION DETECTOR -- 12.8. ELECTROLYTIC CONDUCTIVITY DETECTOR -- 12.9. ATOMIC EMISSION DETECTOR -- 12.10. CHEMILUMINESCENT DETECTOR -- References -- Chapter 13 - Hyphenated Spectroscopic Detectors for Gas Chromatography -- 13.1. INTRODUCTION -- 13.2. GC INTERFACES -- 13.3. DATA ANALYSIS -- 13.4. GC-ATOMIC EMISSION-MASS SPECTROMETRY -- 13.5. SPECTROSCOPIC DETECTORS FOR GC -- References -- Chapter 14 - Plasma-Based Gas Chromatography Detectors -- 14.1. INTRODUCTION TO PLASMA-BASED DETECTORS -- 14.2. GC-ICPMS -- 14.3. GC-MIP AND GC-GD -- 14.4. SAMPLE PREPARATION FOR GC-PLASMA SPECTROSCOPY -- 14.5. ADVANCES IN APPLICATIONS OF GC-PLASMA SPECTROSCOPY -- 14.6. CONCLUSIONS AND PERSPECTIVES -- References -- Chapter 15 - Field and Portable Instruments -- 15.1. HISTORY -- 15.2. DESIGN CHALLENGES -- 15.3. SAMPLE INTRODUCTION -- 15.4. COLUMN CONFIGURATIONS -- 15.5. DETECTORS -- 15.6. GAS SUPPLY -- 15.7. POWER MANAGEMENT -- 15.8. PROTOTYPING -- 15.9. FUTURE TRENDS -- References -- Chapter 16 - Preparative Gas Chromatography -- 16.1. INTRODUCTION.

16.2. APPLICATION SCALE OF PREPARATIVE GAS CHROMATOGRAPHY -- 16.3. EXPERIMENTAL TECHNIQUES FOR ANALYTICAL-SCALE PREP-GC -- 16.4 CASE STUDIES: APPLICATIONS -- 16.5 CONCLUSIONS -- References -- Chapter 17 - Data Analysis Methods -- 17.1. INTRODUCTION -- 17.2. PREPROCESSING -- 17.3. PATTERN RECOGNITION -- 17.4. CALIBRATION -- 17.5. EXPERIMENTAL METHOD OPTIMIZATION -- 17.6. CONCLUSION -- References -- Chapter 18 - Validation of Gas Chromatographic Methods -- 18.1. INTRODUCTION -- 18.2. REGULATORY ASPECTS -- 18.3. METHOD VALIDATION ITEMS -- 18.4. ACCURACY PROFILES -- 18.5. CONCLUSIONS -- References -- Chapter 19 - Quantitative Structure-Retention Relationships -- 19.1. INTRODUCTION -- 19.2. HISTORICAL PERSPECTIVE -- 19.3. MOST FREQUENT ERRORS -- 19.4. RECOMMENDATIONS TO AVOID THE MOST COMMON ERRORS -- 19.5. CORRECT VALIDATION -- 19.6. RECENT DEVELOPMENTS -- References -- Chapter 20 - Physicochemical Measurements (Inverse Gas Chromatography) -- 20.1. GAS-SOLID IGC -- 20.2. BULK PROPERTIES OF POLYMERS AND POLYMER BLENDS -- References -- Chapter 21 - Separation of Enantiomers -- 21.1. INTRODUCTION -- 21.2. CHIRAL STATIONARY PHASES BASED ON α-AMINO ACID DERIVATIVES -- 21.3. CHIRAL STATIONARY PHASES BASED ON METAL CHELATES -- 21.4. CHIRAL STATIONARY PHASES BASED ON MODIFIED CYCLODEXTRINS (CDS) -- 21.5. THE TEMPERATURE DEPENDENCE OF ENANTIOSELECTIVITY, ENTHALPY/ENTROPY COMPENSATION, AND THE ISOENANTIOSELECTIVE TEMPERA ... -- 21.6. APPLICATIONS -- 21.7. HYPHENATED APPROACHES IN ENANTIOSELECTIVE GC -- 21.8. TWO-DIMENSIONAL APPROACHES IN ENANTIOSELECTIVE GC -- 21.9. ENANTIOSELECTIVE STOPPED-FLOW MULTIDIMENSIONAL GAS CHROMATOGRAPHY (SF-MDGC) -- 21.10. PRACTICAL ASPECTS OF ENANTIOSELECTIVE GC -- 21.11. (SEMI)PREPARATIVE-SCALE ENANTIOSEPARATIONS BY GC -- References -- Chapter 22 - Analysis of Essential Oils and Fragrances by Gas Chromatography.

22.1. DEFINITIONS: WHAT IS ESSENTIAL OIL? WHAT ARE FRAGRANCES? -- 22.2. GC PHASES USED IN THE ANALYSIS OF ESSENTIAL OILS AND AROMA CHEMICALS -- 22.3. SEPARATION CRITERIA AND TECHNIQUES -- 22.4. RETENTION INDEX -- 22.5. QUALITATIVE AND QUANTITATIVE ASPECTS -- 22.6. GC-MS LIBRARIES -- 22.7. CONCLUSIONS -- References -- Chapter 23 - Analysis of Lipids by Gas Chromatography -- 23.1. INTRODUCTION -- 23.2. FATTY ACID ANALYSIS BY GC AS METHYL ESTER DERIVATIVES -- 23.3. ANALYSIS OF FREE FATTY ACIDS -- 23.4. ANALYSIS OF ACYLGLYCEROLS -- 23.5. ANALYSIS OF STEROLS, STEROL ESTERS, AND STERYL GLYCOSIDES -- 23.6. ANALYSIS OF WAXES -- 23.7. ANALYSIS OF LIPID CLASSES -- References -- Chapter 24 - Metabonomics -- 24.1. OVERVIEW OF METABONOMICS -- 24.2. ANALYTICAL TOOLS IN METABONOMIC RESEARCH -- 24.3. GC-MS-BASED METABONOMICS -- 24.4. GC-MS-BASED TISSUE METABONOMICS -- 24.5. GC-MS-BASED URINE METABONOMICS -- 24.6. FUTURE DIRECTIONS -- 24.7. CONCLUSION -- References -- Chapter 25 - Applications of Gas Chromatography in Forensic Science -- 25.1. INTRODUCTION AND SCOPE -- 25.2. ANALYSIS OF BULK DRUG FOR IDENTIFICATION, IMPURITY PROFILING, AND DRUG INTELLIGENCE PURPOSE -- 25.3. GAS CHROMATOGRAPHY IN FORENSIC TOXICOLOGY -- 25.4. ANALYSIS OF IGNITABLE LIQUID RESIDUES FROM FIRE DEBRIS -- 25.5. ANALYSIS OF EXPLOSIVES -- 25.6. GAS CHROMATOGRAPHIC ANALYSIS OF ORGANIC GUNSHOT RESIDUES (OGSRS) -- 25.7. ANALYSIS OF FORENSIC TRACE EVIDENCE -- 25.8. FORENSIC ENVIRONMENTAL ANALYSIS -- 25.9. ANALYSIS OF HUMAN ODOR PROFILE -- 25.10. ANALYSIS OF HUMAN DECOMPOSITION PRODUCTS -- 25.11. FIELD-PORTABLE GAS CHROMATOGRAPH FOR ONSITE SAMPLE ANALYSIS -- 25.12. GAS CHROMATOGRAPHY IN FOOD FORENSICS -- 25.13. ANALYSIS OF CHEMICAL WARFARE AGENTS (CWAS) -- 25.14. NEW DEVELOPMENTS IN GAS CHROMATOGRAPHY WITH FORENSIC IMPLICATIONS -- 25.15. CONCLUSIONS -- References.

Chapter 26 - Application of Gas Chromatography to Multiresidue Methods for Pesticides and Related Compounds in Food.