Evidence-Based Pediatric Oncology -- Copyright -- Contents -- List of contributors -- Preface -- List of abbreviations -- About the companion website -- Part 1: Solid tumors -- Chapter 1 Rhabdomyosarcoma -- Commentary by Meriel Jenney -- Philosophy of treatment of rhabdomyosarcoma -- Treatment: the general approach -- Lessons from studies of rhabdomyosarcoma -- Lessons from studies of nonrhabdomyosarcoma soft tissue sarcomas -- Conclusion -- References -- Summary of previous studies -- References -- New studies -- Study 1 -- Study 2 -- Chapter 2 Osteosarcoma -- Commentary by Maria Michelagnoli -- References -- Summary of previous studies -- References -- New studies -- Study 1 -- Study 2 -- Study 3 -- Chapter 3 Ewing sarcoma -- Commentary by Steven G. DuBois -- References -- Summary of previous studies -- References -- New studies -- Study 1 -- Study 2 -- Study 3 -- Study 4 -- Study 5 -- Study 6 -- Study 7 -- Chapter 4 Wilms tumor -- Commentary by Kathy Pritchard-Jones -- References -- Summary of previous studies -- References -- New studies -- Study 1 -- Study 2 -- Study 3 -- Chapter 5 Neuroblastoma -- Commentary by Katherine K. Matthay -- References -- Summary of previous studies -- References -- New studies -- Study 1 -- Study 2 -- Study 3 -- Study 4 -- Study 5 -- Study 6 -- Chapter 6 Hepatoblastoma -- Commentary by Penelope Brock -- References -- Summary of previous studies -- References -- New studies -- Study 1 -- Study 2 -- Chapter 7 Malignant germ cell tumors -- Commentary by Ross Pinkerton -- References -- Summary of previous studies -- References -- New studies -- Chapter 8 Medulloblastoma -- Commentary by Eric Bouffet -- Early randomized studies -- Recent medulloblastoma trials -- Future directions -- References -- Summary of previous studies -- References -- New studies -- Study 1 -- Study 2 -- Study 3 -- Chapter 9 Glioma.

Commentary by Joann L. Ater -- Radiation therapy -- Chemotherapy -- Conclusions -- References -- Summary of previous studies -- References -- New studies -- Chapter 10 Non-Hodgkin lymphoma -- Commentary by Ross Pinkerton -- References -- Summary of previous studies -- References -- New studies -- Study 1 -- Study 2 -- Study 3 -- Study 4 -- Chapter 11 Hodgkin lymphoma -- Commentary by Cindy L. Schwartz -- Radiation therapy -- Combination therapy -- Chemotherapy only -- References -- Summary of previous studies -- References -- New studies -- Study 1 -- Study 2 -- Part 2: Leukemia -- Section 1: Acute myeloid leukemia -- Chapter 12 Acute myeloid leukemia commentary -- Induction -- Postremission therapy -- References -- Chapter 13 Remission induction in acute myeloid leukemia -- Summary of previous studies -- References -- New studies -- Study 1 -- Study 2 -- Study 3 -- Study 4 -- Chapter 14 Acute myeloid leukemia consolidation -- New study -- Study 1 -- Chapter 15 Maintenance treatment in acute myeloid leukemia -- Summary of previous studies -- References -- New studies -- Chapter 16 Autologous bone marrow transplantation in acute myeloid leukemia -- Summary of previous studies -- References -- New studies -- Chapter 17 Acute myeloid leukemia: miscellaneous -- New study -- Study 1 -- Section 2: Childhood lymphoblastic leukemia -- Chapter 18 Childhood lymphoblastic leukemia commentary -- Remission induction -- Postinduction therapy -- Continuation therapy -- Minimal residual disease -- Relapsed acute lymphoblastic leukemia -- Long-term effects -- New agents -- References -- Chapter 19 Remission induction in childhood lymphoblastic leukemia -- Summary of previous studies -- References -- New studies -- Study 1 -- Study 2 -- Study 3 -- Study 4 -- Study 5 -- Study 6 -- Study 7.

Chapter 20 Central nervous system-directed therapy in childhood lymphoblastic leukemia -- Summary of previous studies -- Dose of irradiation -- The need for irradiation in central nervous system-directed therapy -- Schedule of irradiation -- Type of intrathecal therapy and duration of treatment -- Role of intermediate- and high-dose methotrexate -- Role of high-dose cytarabine -- Overview -- References -- New studies -- Chapter 21 Maintenance treatment in childhood lymphoblastic leukemia -- Summary of previous studies -- Duration of therapy -- Pulses of steroids and vincristine -- Dose and route of methotrexate -- Drug schedule -- Type of thiopurine -- Addition of other drugs during continuing therapy -- References -- New studies -- Pulses of vincristine and steroids -- Study 1 -- Study 2 -- Drug schedule -- Study 3 -- Study 4 -- Study 5 -- Type of thiopurine -- Study 6 -- Study 7 -- Study 8 -- Addition of other drugs during continuing therapy: role of intermediate-/high-dose cytarabine -- Study 9 -- Chapter 22 Relapsed childhood lymphoblastic leukemia -- New studies -- Study 1 -- Study 2 -- Study 3 -- Study 4 -- Chapter 23 Postinduction therapy in adolescents and young adults with acute lymphoblastic leukemia -- New studies -- Study 1 -- Study 2 -- Part 3: Supportive care in pediatric oncology -- Chapter 24 Colony-stimulating factors -- Commentary by Victoria Grandage -- References -- Summary of previous studies -- Granulocyte colony-stimulating factor -- References -- Granulocyte macrophage colony-stimulating factor -- References -- Erythropoietin -- References -- New studies -- Study 1 -- Study 2 -- Study 3 -- Study 4 -- Study 5 -- Study 6 -- Chapter 25 Cardioprotection in pediatric oncology -- Commentary by Gill A. Levitt -- References -- Summary of previous studies -- References -- New studies -- Adverse effects of cardioprotectant (dexrazoxane).

Study 1 -- Study 2 -- Study 3 -- Efficacy of anthracyclines in pediatric oncology -- Study 4 -- Study 5 -- Chapter 26 Infections in pediatric and adolescent oncology -- Commentary by Julia E. Clark -- Introduction -- Risk stratification -- Fungal infection -- Central venous catheter infections -- New studies -- Fungal infections -- Study 1 -- Study 2 -- Study 3 -- Study 4 -- Study 5 -- Bacterial infections -- Study 6 -- Study 7 -- Study 8 -- Study 9 -- Study 10 -- Study 11 -- Study 12 -- Study 13 -- Study 14 -- Study 15 -- Study 16 -- Study 17 -- Line infections -- Study 18 -- Study 19 -- Study 20 -- Index.