Front Cover -- Characterization of Biomaterials -- Copyright -- Contents -- Preface -- List of Contributors -- Chapter 1 - Introduction to Biomaterials -- 1.1. INTRODUCTION -- 1.2. TYPES OF MATERIALS -- 1.3. BIOMATERIALS AND BIOCOMPATIBILITY -- 1.4. TYPES OF BIOMATERIALS -- 1.5. PROPERTIES OF BIOMATERIALS -- 1.6. BIOMATERIALS CHARACTERIZATION AND OUTLINE OF THIS BOOK -- 1.7. SUMMARY -- SUGGESTED FURTHER READING -- Chapter 2 - Physical and Chemical Characterization of Biomaterials -- 2.1. MICROSTRUCTURAL CHARACTERIZATION -- 2.2. SCANNING PROBE MICROSCOPY -- 2.3. X-RAY DIFFRACTION AND SCATTERING METHODS -- 2.4. FT-IR SPECTROSCOPY -- 2.5. DLS TECHNIQUES -- 2.6. CONTACT ANGLE MEASUREMENTS -- 2.7. MERCURY INTRUSION POROSIMETRY -- 2.8. GAS ADSORPTION MEASUREMENTS -- 2.9. SUMMARY -- REFERENCES -- Chapter 3 - Mechanical Characterization of Biomaterials -- 3.1. INTRODUCTION -- 3.2. FUNDAMENTAL CONCEPTS -- 3.3. SPECIMENS -- 3.4. APPLICATION AND MEASUREMENT OF LOAD AND DEFORMATION -- 3.5. ENVIRONMENT -- 3.6. DATA ACQUISITION AND ANALYSIS -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 4 - Surface Characterization of Biomaterials -- 4.1. X-RAY PHOTOELECTRON SPECTROSCOPY -- 4.2. AUGER ELECTRON SPECTROSCOPY -- 4.3. Secondary Ion Mass Spectrometry (SIMS) -- 4.4. SURFACE MATRIX-ASSISTED LASER DESORPTION IONIZATION MASS SPECTROMETRY -- 4.5. INFRARED (IR) SPECTROSCOPY -- 4.6. RAMAN SPECTROSCOPY -- 4.7. ELECTRON ENERGY LOSS SPECTROSCOPY -- 4.8. ULTRAVIOLET-VISIBLE SPECTROSCOPY -- 4.9. LIGHT MICROSCOPY AND CONFOCAL MICROSCOPY -- 4.10. SCANNING ELECTRON MICROSCOPY -- 4.11. SCANNING TUNNELLING MICROSCOPY AND ATOMIC FORCE MICROSCOPY -- 4.12. PROFILOMETRY -- 4.13. CONTACT ANGLE MEASUREMENT -- 4.14. ELLIPSOMETRY -- 4.15. CONCLUSIONS -- REFERENCES -- Chapter 5.1 - In Vitro Characterization of Cell-Biomaterials Interactions -- 5.1.1. INTRODUCTION.

5.1.2. BASICS OF CELL BIOLOGY -- 5.1.3. MATERIALS FOR BIOMEDICAL APPLICATIONS (BIOMATERIALS) -- 5.1.4. CELL-NANOTOPOGRAPHY RESPONSES ON SYNTHETIC SUBSTRATES -- 5.1.5. TECHNIQUES TO EVALUATE CELL-MATERIAL INTERACTIONS -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 5.2 - Characterization of Bacteria-Biomaterial Interactions, from a Single Cell to Biofilms -- 5.2.1. INTRODUCTION -- 5.2.2. QUANTIFICATION OF BACTERIAL INTERACTIONS WITH SURFACES -- 5.2.3. ATOMIC FORCE MICROSCOPY (AFM) USE IN INVESTIGATIONS OF BIOLOGICAL SYSTEMS -- 5.2.4. USE OF AFM FOR QUANTIFICATION OF BACTERIA-BIOMATERIAL INTERACTIONS -- 5.2.5. EXAMPLES FROM THE LITERATURE OF AFM STUDIES OF BACTERIA-BIOMATERIAL INTERACTIONS -- 5.2.6. CHARACTERIZATION OF BIOFILMS ON BIOMATERIAL SURFACES -- 5.2.7. QUANTIFYING BIOFILM STRUCTURE -- 5.2.8. ANALYSIS OF BIOFILM IMAGES -- 5.2.9. CONCLUSIONS -- SOURCES FOR FURTHER INFORMATION AND ADVICE -- ACKNOWLEDGMENTS -- REFERENCES -- Chapter 6 - In Vivo Characterization of Biomaterials -- 6.1. INTRODUCTION -- 6.2. IDEAL CHARACTERISTICS OF BIOMATERIAL FOR IN VIVO APPLICATION -- 6.3. ANIMAL MODEL IN ORTHOPAEDIC SURGERY -- 6.4. ANIMAL MODELS IN SPINAL SURGERY AND CHARACTERIZATION OF BIOMATERIALS -- 6.5. CHARACTERIZATION PARAMETERS -- 6.6. BIODISTRIBUTION STUDIES -- 6.7. IN VIVO CHARACTERIZATION OF BIOMATERIALS IN SOFT TISSUE SURGERY -- 6.8. SUMMARY -- REFERENCES -- Chapter 7.1 - Structural and Biological Characterization of Scaffolds -- 7.1.1. INTRODUCTION -- 7.1.2. CHARACTERIZATION OF SCAFFOLDS MORPHOLOGY AND POROSITY -- 7.1.3. PERMEABILITY -- 7.1.4. MECHANICAL CHARACTERIZATION OF SCAFFOLDS -- 7.1.5. BIOLOGICAL CHARACTERIZATION OF SCAFFOLDS -- 7.1.6. SUMMARY -- REFERENCES -- Chapter 7.2 - Mechanical Properties of Bioceramic Coatings on Medical Implants -- 7.2.1. INTRODUCTION -- 7.2.2. COATING MICROSTRUCTURE -- 7.2.3. WEAR PROPERTIES.

7.2.4. BOND STRENGTH OF COATINGS -- 7.2.5. FATIGUE PROPERTIES OF COATINGS -- 7.2.6. SHEAR TESTING OF COATINGS -- 7.2.7. SUMMARY -- REFERENCES -- Chapter 8 - Characterization of Orthopaedic Devices -- 8.1. MECHANICAL TESTING OF ORTHOPAEDIC DEVICES -- 8.2. TRIBOLOGICAL TESTING OF JOINT IMPLANTS -- 8.3. METALLIC COATINGS FOR ORTHOPAEDIC DEVICES -- REFERENCES -- Chapter 9 - Characterization of Cardiovascular Implantable Devices -- 9.1. CARDIOVASCULAR SYSTEM -- 9.2. TYPES OF CARDIOVASCULAR IMPLANTABLE DEVICES -- 9.3. IN VITRO CHARACTERIZATION OF CARDIOVASCULAR IMPLANTABLE DEVICES -- REFERENCES -- Index.