Radiation Oncology in Palliative Cancer Care.
Title:
Radiation Oncology in Palliative Cancer Care.
Author:
Lutz, Stephen.
ISBN:
9781118607169
Personal Author:
Edition:
1st ed.
Physical Description:
1 online resource (410 pages)
Contents:
Cover -- Title page -- Copyright page -- Contents -- Contributor list -- Foreword -- PART 1: General principles of radiation oncology -- CHAPTER 1: A brief history of palliative radiation oncology -- Introduction -- The early years -- Fractionation -- Advances in radiotherapy technique: the 1950s and 1960s -- Fractionation revisited: explicit palliation -- Stereotactic radiotherapy -- Prognostication and tailoring palliative radiotherapy to anticipated survival -- Conclusion -- References -- CHAPTER 2: The radiobiology of palliative radiation oncology -- Introduction -- Radiation effect on cells -- Direct and indirect effect of radiation -- Shape of the cell survival curves -- Cell cycle characteristics -- Interaction of cell cycle and radiotherapy fractionation -- Radiotherapy fractionation characteristics -- Conclusion -- References -- CHAPTER 3: The physics of radiation oncology -- Introduction -- The development of radiation therapy technology -- The early understanding of radiation therapy -- The development of teletherapy machines -- The proliferation of linear accelerators -- The advent of intensity modulated radiation therapy -- Brachytherapy radiation -- The impact of diagnostic improvements on radiotherapy delivery -- Process of radiation therapy -- Simulation -- Dosimetry -- Initiation of therapy -- Patient immobilization -- Management of patients during treatment -- Special considerations in developing countries -- Conclusion -- References -- CHAPTER 4: Curative intent versus palliative intent radiation oncology -- Introduction -- The determination of cure plus palliation intent versus pure palliative intent -- Clinical diagnoses -- High grade glioma -- Pancreatic and biliary tract cancer -- Lung cancer -- Esophageal cancer -- Gynecologic malignancies -- Genitourinary cancer -- Gastric cancer -- Colorectal cancer.
Advanced head and neck cancers -- Special considerations in developing countries -- Conclusion -- References -- CHAPTER 5: Side effects of palliative radiotherapy -- Introduction -- Issues with interpreting palliative radiotherapy toxicity data -- Acute side effects -- General -- Fatigue -- Hematologic -- Skin and bone -- Head and neck -- Thorax -- Abdomen and pelvis -- Central nervous system (CNS) -- Late side effects -- General -- Fatigue -- Skin and bone -- Thorax -- Abdomen and pelvis -- Central nervous system -- Second malignancies -- Additive toxicity -- Clinical advice -- New technologies -- Challenges in developing countries -- Conclusion -- References -- PART 2: General principles of palliation and symptom control -- CHAPTER 6: A history of hospice and palliative medicine -- Introduction -- Before the modern movement -- St. Christopher's and the modern hospice -- Palliative care in the United States -- Global development of hospice and palliative care -- Continuing challenges -- References -- CHAPTER 7: Radiation therapy and hospice care -- Introduction -- Hospice care around the world -- Hospice care in the United States -- Prognosis -- Plan of care (POC) -- Physician role -- Places of care -- Payment to the hospice -- Palliative radiation and hospice -- Conclusion -- References -- CHAPTER 8: The current status of palliative care and radiotherapy -- What is palliative care? -- Who can benefit from palliative care? -- What are the goals of palliative care and what features of a palliative care program help to accomplish these goals? -- What is the evidence regarding the benefits and risks of palliative care? When should palliative care be introduced to a patient? -- Are there standards for palliative care? If so, what are the defining measures? -- How does palliative care fit in with radiation oncology? -- References.
CHAPTER 9: Palliative care in low and middle income countries: A focus on sub-Saharan Africa -- Introduction -- The need for palliative care -- Radiotherapy -- Specific clinical indications for palliative radiotherapy in Africa -- Kaposi sarcoma -- Cervical cancer -- Challenges of palliative care delivery -- Addressing challenges to adequate palliative care -- Palliative care in medical training curricula -- Leadership -- The role of governments -- Palliative care research -- Delivery of palliative care -- Conclusion -- References -- CHAPTER 10: Pain management -- Introduction -- Pain assessment -- Analgesia ladder -- Primary pharmacologic interventions -- Non-steroidal anti-inflammatory drugs -- Opioids -- Adjuvant medications -- Steroids -- Anti-epileptics -- Anti-depressants -- End-of-life considerations -- Conclusion -- References -- PART 3: Locally advanced or locally recurrent diseases -- CHAPTER 11: Primary tumors of the central nervous system -- Introduction -- Incidence/prevalence, at-risk populations -- Symptoms -- Survival -- Radiotherapy -- Elderly and poor prognosis patients -- Recurrent tumor after prior irradiation -- Radiosurgery -- Hypofractionated radiotherapy -- Side-effect risks -- Acute -- Late -- Radiotherapy limitations -- Adjuvant treatment modalities -- Radiotherapy combined with systemic therapy -- Promise of newer technologies -- Radioimmunotherapy -- Special considerations in developing countries -- Conclusion -- References -- CHAPTER 12: The role of palliative care in head and neck cancer -- Introduction -- Current management of head and neck squamous cell carcinomas -- Patient selection for palliative treatment -- Use of palliative radiotherapy in head and neck squamous cell carcinomas -- Recurrent disease -- The promise of emerging technologies -- Chemotherapy in palliative head and neck squamous cell carcinomas.
Non-squamous cell carcinomas histologies -- Specific issues in palliation of head and neck squamous cell carcinomas -- Special considerations in developing countries -- Conclusion -- References -- CHAPTER 13: The role of palliative radiotherapy in breast cancer -- Introduction -- Rates of palliative loco-regional radiotherapy -- Biologic considerations -- Definitions, clinical features, and multi-disciplinary approach -- Clinical scenarios -- Locally advanced disease -- Flap recurrence after mastectomy -- Recurrence within a previously irradiated area -- Hyperthermia with or without additional radiotherapy or systemic therapy -- Axillary recurrence and brachial plexopathy -- Supraclavicular node metastases -- Symptom control -- Bleeding -- Ulceration, discharge, and infection -- Palliative loco-regional radiotherapy for oligometastatic disease -- Radiotherapy dosing schedules -- Standard dose fractionation -- Alternative fractionation -- Radiotherapy technique and the promise of newer technology -- Special considerations in developing countries -- Follow up -- Conclusion -- References -- CHAPTER 14: Palliative radiotherapy in advanced lung cancer -- Introduction -- Radiotherapy treatment -- Overview -- External beam dose fractionation -- Endobronchial brachytherapy -- Concurrent chemotherapy integrated with palliative thoracic radiotherapy -- The impact of emerging technologies -- Important circumstances -- Patient selection -- Patient preferences -- Economic considerations -- Special considerations in developing countries -- Resource constrained practice -- Conclusion -- References -- CHAPTER 15: Palliative radiotherapy for gastrointestinal and colorectal cancer -- Introduction -- Treatment of dysphagia -- Gastric cancer -- Palliation of biliary obstruction -- Nodes at origin of the superior mesenteric artery -- High dose rate brachytherapy.
Locally advanced/recurrent rectal cancer -- Re-irradiation -- Anal cancer -- The promise of highly conformal therapy -- Special considerations in developing countries -- Conclusion -- References -- CHAPTER 16: Genitourinary malignancies -- Introduction -- Incidence and etiology -- Clinical behavior -- Bladder cancer -- Prostate cancer -- Renal cancer -- Palliative radiotherapy and other approaches for management of primary disease -- Bladder cancer -- Prostate cancer -- Renal cancer -- Other approaches -- Specific management of metastatic disease in urologic malignancies -- Prostate cancer -- Renal cancer -- The promise of highly conformal therapy -- Special considerations in developing countries -- Conclusion -- References -- CHAPTER 17: Palliative radiotherapy in locally advanced and locally recurrent gynecologic cancer -- Introduction -- Patterns of loco-regional failures for gynecologic cancers -- Management -- Treatment of recurrent carcinoma of the cervix -- Recurrence after definitive radiation -- Recurrence after definitive surgery -- The promise of newer technologies -- Special considerations in developing countries -- Conclusion -- References -- CHAPTER 18: Hematologic malignancies and associated conditions -- Introduction -- Diagnoses -- Specific clinical circumstances -- Large bulky lymph nodes -- Enlarged spleen -- Chloromas (granulocytic sarcoma) -- Osseous involvement by plasma cell malignancies -- Locally advanced and recurrent disease -- Future directions -- Special considerations in developing countries -- Conclusion -- References -- CHAPTER 19: Pediatric palliative radiation oncology -- Introduction -- Delivery of radiation treatment -- Differences between pediatric and adult populations -- Background -- Clinical indications for palliative radiotherapy -- Superior vena cava syndrome and superior mediastinal syndrome.
Bone and soft tissue metastases.
Abstract:
"This textbook, Radiation Oncology in Palliative Cancer Care, represents the full evolution of radiation therapy, and of oncology in general. ( … ) [It] is an acknowledgment that palliative radiotherapy is now a sub-specialty of radiation oncology. This formally makes palliative radiotherapy a priority within patient care, academic research, quality assurance, and medical education." - From the Foreword by Nora Janjan, MD, MPSA, MBA, National Center for Policy Analysis, Dallas, TX, USA Palliative Medicine is the professional medical practice of prevention and relief of suffering and the support of the best possible quality of life for patients and their families, regardless of the stage of the disease or the need for other therapies. The most common cause for palliative care referral is terminal cancer, and a large proportion of those referrals include patients who will need palliative radiotherapy during the course of their disease. Still, there are barriers to coordinated care between radiation oncologists and palliative care physicians that differ from one country to another. Until now, one overarching limitation to appropriate concurrent care between the specialties across all countries has been the lack of a comprehensive yet concise reference resource that educates each of the specialties about the potential synergistic effects of their cooperation. This book fills that void. Radiation Oncology in Palliative Cancer Care: Is the first book-length treatment of this important topic available on the market Is authored by world-renowned experts in radiation oncology and palliative medicine Uses a multidisciplinary approach to content and patient treatment Features decision trees for palliative radiotherapy based upon factors such as patient performance status and prognosis Pays careful attention to current best practices and controversies
in the delivery of end-of-life cancer care This book is an important resource for practicing radiation oncologists and radiation oncologists in training, as well as hospice and palliative medicine physicians and nurses, medical oncologists, and geriatricians.
Local Note:
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2017. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
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