Title Page -- Contents -- Preface -- Chapter 1 Epidemiology and Pathogenesis of Type 2 Diabetes -- The current prevalence of diabetes -- Factors driving the type 2 diabetes epidemic -- Pathogenesis of type 2 diabetes -- References -- Chapter 2 Overview of Current Diabetes Management -- Recommended targets for glycaemic control -- Pros and cons of existing non-insulin antidiabetes therapies -- Why are new drugs needed for the treatment of type 2 diabetes? -- References -- Chapter 3 The Incretin System -- References -- Chapter 4 The Incretin Mimetics -- Exenatide -- Liraglutide -- Place in therapy of the incretin mimetics -- References -- Chapter 5 Dipeptidyl Peptidase-4 Inhibitors -- Mechanism of action -- DPP-4 inhibitor clinical efficacy -- Vildagliptin -- Saxagliptin -- DPP-4 inhibitor safety and tolerability -- DPP-4 inhibitor advantages and disadvantages -- DPP-4 inhibitor current indications -- Place in therapy of the DPP-4 inhibitors -- References -- Chapter 6 Sodium-glucose Cotransporter-2 Inhibitors -- Dapagliflozin -- Safety and tolerability -- SGLT-2 inhibitor advantages and disadvantages -- References -- Chapter 7 Pipeline Diabetes Therapies -- Taspoglutide -- Linagliptin -- Bile acid receptor agonists -- Glucokinase activators -- Sirtuins -- Sodium-glucose cotransporter-1 inhibitors -- Sodium-glucose cotransporter-2 antisense inhibitors -- Glucose-dependent insulinotropic polypeptide agonists and antagonists -- Glucagon receptor antagonists -- References -- Chapter 8 Bariatric Surgery for the Treatment of Type 2 Diabetes -- Potential mechanisms of diabetes resolution after bariatric surgery -- Efficacy of bariatric surgery for the treatment of type 2 diabetes -- Considerations -- References -- Chapter 9 Organization of Diabetes Care -- Managing diabetes in primary care -- Delivery of diabetes care closer to home.

Structured patient education programmes -- References -- Index.