Cover image for Abdominal Organ Retrieval and Transplantation Bench Surgery.
Abdominal Organ Retrieval and Transplantation Bench Surgery.
Title:
Abdominal Organ Retrieval and Transplantation Bench Surgery.
Author:
Oniscu, Gabriel.
ISBN:
9781118513149
Personal Author:
Edition:
1st ed.
Physical Description:
1 online resource (194 pages)
Contents:
Abdominal Organ Retrieval and Transplantation Bench Surgery -- Copyright -- Contents -- List of Contributors -- Foreword -- Preface -- About the Companion Website -- 1 Organ Retrieval Logistics -- Introduction -- Diagnosis of death - DBD and DCD donation -- Donation after brain death (DBD) -- Death following cessation of cardiorespiratory function - DCD donation -- Evolution of organ donation and the legal framework governing organ donation -- Organ retrieval teams and organ transplantation units -- Donor coordinators -- Organ retrieval teams -- Transplant units -- Patient selection for transplantation and allocation of deceased donor organs for transplantation -- Patient selection -- Allocation of deceased donor organs for transplantation -- References -- 2 Strategies in Preservation of Abdominal Organs -- Introduction -- A touch of preservation history -- Donor related organ injury -- Some basic principles in organ preservation -- Induction of hypothermia -- Prevention of oedema -- Prevention of acidosis -- Neutralize the formation of reactive oxygen species -- Hypothermia is still a key factor -- Interstitial and cellular oedema -- Cellular acidosis -- Formation of oxygen free radicals -- Preservation solutions -- The static cold storage method of organ preservation -- Machine perfusion revisited: a renaissance in preservation? -- Practical consequences to consider during retrieval -- Packaging of donor organs -- A brief outlook on future practice -- References -- 3 Management of the Brainstem Dead Organ Donor -- Physiological changes associated with brainstem death -- Organ damage -- Clinical management and use of guidelines -- Early guidelines -- Standardization and wider application -- A practical approach to brainstem dead donor management -- Initial assessment and management -- Respiratory management -- Cardiovascular management.

Hormonal changes -- Fluid and electrolyte management -- Blood and coagulation -- Physiological support in the operating theatre -- Implementation and outcomes -- Future research and development of guidelines -- References -- 4 Multiorgan Retrieval -- Introduction -- Retrieval team -- Retrieval logistics -- Pre-retrieval checks -- Multiorgan retrieval technique in DBD donors -- Technical variations -- Retrieval technique -- Perfusion fluids -- In situ perfusion -- Bench perfusion -- Bench surgery -- Separation of the liver-ancreas block -- Kidney bench surgery -- Packing of organs -- Paperwork and documentation -- References -- 5 Kidney Retrieval and Bench Surgery -- General principles and logistics -- Access -- Anatomical variations -- Awareness of common injuries -- Atheroma -- Avulsion -- Procedure -- Immediate bench check -- Special considerations with kidney retrieval -- Removal of peri-renal fat -- Rewarming -- Most common forms of damage following kidney retrieval -- Polar artery cut/patch removed from artery of an aortic patch -- Capsular damage -- Rewarming of kidney -- Ureter cut short or 'skinned' -- Bench surgery for the kidney -- Dealing with common bench surgery problems -- Capsule -- Vein -- Artery -- Ureter -- Pre-implantation biopsy -- Donation after cardiac death and kidney retrieval -- References -- 6 Liver Retrieval and Bench Surgery -- Liver retrieval -- Donor information -- Liver assessment -- Technical aspects of liver retrieval -- Variant arterial anatomy scenarios and solutions -- Bench surgery -- Donor information -- Set-up for bench surgery -- Liver assessment -- Preparation for implantation -- Dissection of the portal vein -- References -- 7 Deceased Cardiac Donor Liver Retrieval -- Introduction -- Controlled DCD -- Liver, pancreas and kidney -- Liver and lungs -- Normothermic regional perfusion (NRP).

Bench perfusion and packing -- Uncontrolled DCD -- Retrieval procedure technique -- Preservation solutions -- Assessment of DCD liver grafts -- References -- 8 In situ Liver Splitting -- Introduction -- Donor and recipient evaluation -- Surgical techniques -- Bench preparation to separate into the left and right lobe -- References -- 9 Ex situ Liver Splitting -- Introduction -- Selection of the deceased donor -- Recipient selection -- Left lateral liver graft -- Extended right liver graft -- Full right and full left hemiliver grafts -- Technique of the ex situ left lateral split procedure -- Quality -- Anatomy -- Surgical technique of left lateral ex situ split -- Technique of the ex situ full left-full right split procedure -- Hilar dissection -- Outcome of split liver recipients -- Outcome of extended right liver grafts -- Outcome of full right-full left split liver transplantation -- References -- 10 Pancreas Retrieval and Bench Surgery -- Background -- Organ procurement -- Medical background -- Donor procedure -- Organ preservation -- Bench surgery -- Reconstruction of arterial supply -- Preparation of the duodenum -- Peripancreatic tissue -- Root of the mesentery -- Islet transplantation -- References -- 11 Intestinal Retrieval and Bench Surgery -- Introduction -- Intestine donor selection -- Intestine donor preparation -- Isolated intestine grafts (ISO-INT) -- Bench reconstruction -- Liver-intestine grafts (LIV-INT) -- Bench reconstruction -- Multivisceral grafts (MVT) -- Bench reconstruction -- References -- 12 Pediatric Age-Specific Aspects of Retrieval and Bench Surgery -- Introduction -- Donor selection for pediatric solid organ transplantation -- Donor to recipient weight ratio -- Donor to recipient age ratio -- Organ-specific donor criteria -- Relevant aspects for organ procurement and techniques -- Technical aspects.

Whole liver en bloc retrieval -- Relevant aspects for bench procedures -- Kidneys -- Liver -- References -- Index.
Abstract:
Gabriel C. Oniscu MD, FRCS, Consultant Transplant Surgeon, Honorary Clinical Senior Lecturer, Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, UK  John L. Forsythe MD, FRCS, Honorary Professor, Consultant Transplant Surgeon, Transplant Unit, Royal Infirmary of Edinburgh, Edinburgh, UK John Fung MD, PhD, Director, Transplantation Centre, Chair, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH, USA.
Local Note:
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2017. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
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