CONTENTS -- Preface -- Tribute to Prof. Stig Lundqvist -- Opening Report -- Opening Remark -- Opening Address -- Workshop Organization -- Biological Physics: An Overview -- 1 Introduction -- 2 Complex Systems -- 3 The Energy Landscape -- 4 Reactions -- 5 New Physics from Proteins -- 6 Acknowledgments -- Fluctuations and Relaxations in Proteins -- 1 Introduction -- 2 X-ray Structure Determination of Metastable States in Myoglobin -- 3 Mossbauer Absorption Spectroscopy -- 4 Phonon-Assisted Mossbauer Effect -- 5 Mean Square Displacements Obtained from X-ray Structure Analysis -- 6 Protein Specific Motions in the Physiological Regime -- 7 Acknowledgment -- References -- Qualitative Methods in Immunological Modelling -- 1 Introduction -- 2 Cells Perform Chemoreception -- 3 The Immune System -- 4 Two Design Principles for Immune System Recognition -- 5 Shape Space -- 6 What Happens When New Antigen Enters the Organism? -- 7 A Random Flight Model for Somatic Hypermutation -- 8 Mutating Antigens -- 9 Concluding Remarks -- 10 Acknowledgments -- References -- Protein Folding: Physics on Products of Evolution -- 1 The Consistency Principle Revisited -- 2 The Two-State Character of Folding and Unfolding Transition -- 3 The Consistency Principle -- 4 Search for Successful Paths of Folding -- 5 Marginal Stability -- 6 Why Consistent? -- 7 Selection during Evolution -- 8 Consistency is not Perfect -- 9 Principle of Mutational Robustness -- References -- Movements of Molecular Motors -- 1 Introduction -- 2 Different Types of Movements -- 3 Directed Walks of Bound Motors -- 4 Random Walks of Motors and Motor Traffic -- 5 Acknowledgments -- References -- Ligand Migration and Binding in Myoglobin Mutant L29W -- 1 Introduction -- 2 Infrared Spectroscopy of L29W Carbonmonoxy Myoglobin.

3 X-ray Structure Analysis of Low-Temperature Photoproducts -- 4 Why Is Ligand Binding in L29W So Much Slower Than in Native MbCO? -- 5 Acknowledgments -- References -- The Polymer Translocation and Barrier Crossing -- References -- Long Range Interaction between Protein Complexes in DNA Controls Replication and Cell Cycle Progression: The Double Helix and Microtubules Behave like Elastically Braced Strings -- 1 Initiation of DNA replication -- 2 A nonstationary driving reaction -- 3 Nonlocal correlations and long range interaction -- 4 A chemical potential energy -- 5 Comparison with data -- 6 Long range interaction control of DNA replication -- 7 Microtubules and DNA duplex work like elastically braced strings -- 8 Initiation of DNA replication and dynamic instability in MTs -- 9 Summary -- 10 Acknowledgements -- References -- From the Biochemistry of Tubulin to the Biophysics of Microtubules -- 1 Introduction-Microtubules -- 2 Tubulin-The Building Block of a Microtubule -- 3 The Electrostatic Properties -- 4 Variations by Tubulin Isotype -- 5 Conclusions -- 6 Acknowledgments -- References -- Path Integral Approach to Reaction in Complex Environment: A Bottleneck Problem -- 1 Introduction -- 2 The Lagrangian Model -- 3 Bottleneck Problem -- 4 Survival Paths and Correlation Function -- 5 Effective Rate Coefficient and Survival Probability -- 6 Limiting Cases -- 7 Discussion and Conclusion -- 8 Acknowledgements -- References -- Pulsed Radiobiology: Possibilities and Perspectives -- 1 Problems of Flash Radiobiology and Medicine -- 2 Modern Short Pulse X-Ray Sources -- 3 Dense Plasma Focus-Pulsed Powerful Source of Hard Radiation of Different Types -- 4 Portable Dense Plasma Focus for X-Ray Diagnostics in Medicine? -- 5 Dose Versus Dose Power (power flux density).

6 Military Electronics Tests Versus Radiation Disease -- 7 Radiobiology Versus X-Ray Microscopy -- 8 Enzyme Activation and Inactivation Induced by Low Dose/High Dose Power Radiation -- 9 Acknowledgments -- References -- Nonlinear Approach in DNA Science -- 1 Introduction -- 2 DNA as A Physical Dynamical System -- 3 Mathematical Modeling of the Internal DNA Motions -- 4 Applications to Biology -- 5 Applications to Nonlinear Mathematics and Physics -- 6 Conclusions -- References -- Strategies to Study Distribution and Function of Minigenes in Microorganisms -- 1 Introduction -- 2 Results and Models -- 3 Conclusions -- 4 Acknowledgements -- References -- Fractional Brownian Motion: Theory and Application to DNA Walk -- 1 Introduction -- 2 Fractional Brownian Motion -- 3 Multifractional Brownian Motion -- 4 FBM Model of DNA Walk -- 5 Scaling Analysis and Numerical Parameter Estimation -- 6 Conclusion -- 7 Acknowledgements -- References -- Myoglobin - The Smallest Chemical Reactor -- References -- Observing Conformational Changes of Individual RNA Molecules Using Confocal Microscopy -- 1 Introduction -- 2 Experimental Approach -- 3 Results and Discussion -- 4 Conclusions -- 5 Acknowledgments -- References -- Path Integral Approach to a Single Polymer Chain with Excluded Volume Effect -- 1 Introduction -- 2 The Mean Square Distance -- 3 Edwards' Model -- 4 Path Integral Approach -- 5 Discussion and Conclusions -- 6 Acknowledgment -- 7 Appendix -- References -- DNA and Microtubules as Vortex-Strings in Superconductor-Like Dynamics -- 1 Long range interaction between proteins in DNA controls the cell cycle -- 2 Extension to three spatial dimensions -- 2 Elastically braced strings in three spatial dimensions -- 4 Hedgehog cytoskeleton solution from non-Abelian model -- 5 Summary and outlook -- References.

Theory of Stretching Individual Polynucleotide Molecule -- 1 Introduction -- 2 Elastic Properties of Double-Stranded DNA -- 3 Mechanics of Pulling Single-Stranded DNA -- 4 Summary and Conclusions -- 5 Acknowledgements -- References -- The Propagation of Electronic Excitation in Molecular Aggregates -- 1 Introduction -- 2 Exciton Formation -- the CES Approximation -- 3 The Effect of Intra-Monomer Vibrations -- 4 Inclusion of Vibrational Broadening -- 5 Propagation of Excitation -- 6 Conclusions -- References.