Equine Pharmacology -- Copyright -- Contents -- Contributors -- Preface -- Section 1 General Review Section -- Chapter 1 Horse of a different color: Peculiarities of equine pharmacology -- Introduction -- Idiosyncrasies related to route of administration -- Drug interactions -- Veterinary compounding pharmacies -- References -- Chapter 2 Basics of antimicrobial therapy for the horse -- Historical perspective -- The bacterial cell wall -- Antimicrobials versus antibiotics -- Isolate -- Aerobes and anaerobes -- Empirical versus culture and sensitivity-guided treatment -- Spectrum approach for empirical therapy -- Antimicrobial pharmacodynamics -- In vitro sensitivity testing -- Postantibiotic effect (PAE) -- Patterns of microbial killing -- Susceptibility, sensitivity, and resistance -- Antimicrobial drug interactions -- Antimicrobials used in equine medicine -- References -- Chapter 3 Anesthesia and sedation in the field -- Clinical pharmacology of equine anesthetic drugs -- References -- Chapter 4 Clinical application of equine analgesics -- Use of systemic analgesics -- Antispasmodic medications -- Use of intra-articular analgesics -- Epidural administration of analgesic drugs -- Analgesic use in foals -- References -- Chapter 5 Pharmacology of nonsteroidal anti-inflammatory drugs -- The inflammatory cascade -- Indications and use of NSAIDs in horses -- Pharmacokinetics of NSAIDs in horses -- Adverse effects of the use of NSAIDs in horses -- Novel targets of classic NSAIDs -- New NSAIDs -- References -- Chapter 6 Parasiticides for use in horses -- Introduction -- Resistance issues -- Specific anthelmintics -- Broad-spectrum combination anthelmintic products -- General Recommendations -- References -- Chapter 7 Foals are not just mini horses -- Unique aspects of foal pharmacology -- Clinical pharmacology for neonatal diseases.

Gastrointestinal pharmacology: Enteritis, ulcer prophylaxis, and ileus -- Respiratory pharmacology -- Treatment of hypoventilation in neonatal foals -- Seizure control -- References -- Chapter 8 Fluids and electrolytes for the equine clinician -- Principles of fluid therapy -- Identifying patients requiring fluid therapy -- Volume of fluids to administer -- Rate of fluid administration -- Choosing the type of fluid to be administered -- Route of fluid administration -- Practical aspects of fluid therapy -- Monitoring fluid therapy -- Complications of fluid therapy -- Conclusions -- References -- Chapter 9 Drug and medication control programs in equine athletes -- Introduction -- Regulation of equine sport -- Governing authorities -- Practicing within a regulated environment -- Compounded medications -- Over-the-counter products and herbal remedies and supplements -- The drug testing process -- Conclusion -- Reference -- Section 2 Therapeutics: A Systems Approach -- Chapter 10 Clinical pharmacology of the respiratory system -- Respiratory anatomy as it pertains to clinical pharmacology -- Respiratory tract defense system -- Considerations for distribution of drugs to the respiratory system -- Infectious diseases of the LRT -- Noninfectious LRT disease -- Exercise-induced pulmonary hemorrhage (EIPH) -- Infectious diseases of the URT -- Noninfectious diseases of the URT -- References -- Chapter 11 Clinical application of gastrointestinal therapeutics -- Therapy for the equine gastric ulcer syndrome -- Therapy for diarrhea and infectious causes of GI disease -- Therapy for ileus -- References -- Chapter 12 Treatment of equine nervous system disorders -- Introduction -- Central nervous system trauma -- Cervical vertebral stenotic myelopathy -- Equine protozoal myeloencephalitis -- Viral disease of the equine nervous system.

Equine degenerative myelopathy/neuroaxonal dystrophy -- Equine motor neuron disease -- Headshaking -- Cauda equina syndrome -- Equine reflex hypertonia (stringhalt) -- Seizure control and management in horses -- Narcolepsy -- Antimicrobial therapy for CNS infections -- Lyme disease/neuroborreliosis -- Hepatic encephalopathy -- Drugs used for behavioral modification -- References -- Chapter 13 Clinical pharmacology of the equine musculoskeletal system -- Nonsteroidal anti-inflammatory drugs -- Pharmacological approaches for the treatment of navicular syndrome -- Pharmacological approaches to the treatment of laminitis -- Perineural and intra-articular anesthesia (diagnostic blocking for lameness exams) -- Pharmacological management of osteoarthritis -- Medications used for the treatment of epaxial and other muscle pain -- Medications used to treat/prevent rhabdomyolysis -- Medications used in the prevention and management of hyperkalemic periodic paralysis -- Medications used to treat toxin-induced musculoskeletal disorders -- Corynebacterium pseudotuberculosis infections (ulcerative lymphangitis, pigeon fever, pigeon breast) -- Appendicular cellulitis -- Vasculitis and purpura hemorrhagica -- Immune-mediated polymyositis -- Bacteria-associated myositis/myonecrosis -- MRSA infections of the musculoskeletal system -- Drugs used for regional administration and treatment of septic arthritis/osteomyelitis/physitis -- Lyme disease -- References -- Chapter 14 Therapy of the eye -- Ocular anatomy, routes of ocular drug administration, and barriers to drug penetration -- Ophthalmic drug formulation -- Methods of ocular drug delivery -- Drug therapy for examination and diagnostic testing -- Drug therapy for keratitis -- Keratomalacia -- Stromal abscess -- Drug therapy for noninfectious keratitis -- Drug therapy for uveitis -- Drug therapy for glaucoma.

References -- Chapter 15 Pharmacological treatment of equine endocrine diseases -- Introduction -- Equine metabolic syndrome (EMS) -- Pituitary pars intermedia dysfunction (PPID) -- References -- Chapter 16 Equine cardiovascular clinical pharmacology -- Congestive heart failure -- Medical management of cardiac arrhythmias -- Acknowledgment -- References -- Chapter 17 Clinical pharmacology of diseases of the equine urinary system -- Acute renal failure -- Management of acute leptospirosis -- Chronic renal failure -- Therapeutic approaches to urinary incontinence and retention -- Treatment of urinary tract infections -- Therapeutic options for urolithiasis -- References -- Index -- End User License Agreement.