Cover image for Botulinum Neurotoxin Injection Manual.
Botulinum Neurotoxin Injection Manual.
Title:
Botulinum Neurotoxin Injection Manual.
Author:
Alter, Katharine E.
ISBN:
9781617052095
Personal Author:
Physical Description:
1 online resource (369 pages)
Contents:
Cover -- Title -- Copyright -- Contents -- Contributors -- Preface -- Share Botulinum Neurotoxin Injection Manual -- Section One: Botulinum Neurotoxin: Basic Science and Reconstitution -- Chapter 1: Pharmacology of Botulinum Neurotoxins -- Normal Neurotransmitter Release -- BoNTs Synthesis and Structure -- BoNT Binding/Blocking -- BoNT Potency and Dosing -- Clinical Implications of BoNT Pharmacology -- Antigenicity, Antibody Formation, and Nonresponsiveness to BoNT -- Safety -- Central Effects of BoNTs -- Summary -- Chapter 2: Comparison of Botulinum Neurotoxin Products -- BoNT Approvals -- BoNT Products: Antigenicity, Dilution, and Diffusion -- BoNT Products: Potency and Dose -- Converting Units/Dose Among BoNT Products -- Summary -- Chapter 3: Neurotoxin Storage, Reconstitution, Handling, and Dilution -- Serotype B BoNT -- Serotype A BoNTs -- OnabotulinumtoxinA (Botox®) Reconstitution and Handling -- AbobotulinumtoxinA (Dysport®) Reconstitution and Handling -- IncobotulinumtoxinA (Xeomin®) Reconstitution and Handling -- RimabotulinumtoxinB (Myobloc® in the United States, NeuroBloc® Outside the United States) Reconstitution and Handling -- Injection Supplies -- Needle Selection -- Chapter 4: Guidance Techniques for Botulinum Neurotoxin Injections -- Anatomic Reference Guides, Surface Anatomy, and Palpation Guidance -- EMG Guidance -- Electrical Stimulation Guidance -- B-Mode Ultrasound -- Combinations of Techniques -- Other Guidance Techniques for BoNT Injections -- Summary -- Chapter 5: Phenol Nerve Blocks -- Why Consider Phenol Neurolysis? -- Phenol Mechanism of Action -- Muscle Hypertonia -- Pattern of Involvement -- Injection Technique and Dosing -- Musculocutaneous Nerve -- Obturator Nerve -- Tibial Motor Nerves -- Summary -- Section Two: Clinical Applications of Botulinum Neurotoxins.

Part I: Botulinum Neurotoxins for the Treatment of Muscle Overactivity Associated with Focal Dystonia Syndromes and Upper Motor Neuron Syndromes -- Craniofacial Dystonia -- Chapter 6: Benign Essential Blepharospasm -- Chapter 7: Botulinum Neurotoxin Therapy for Hemifacial Spasm -- Chapter 8: Botulinum Neurotoxin Injections for Oromandibular Dystonias -- Illustrations for Craniofacial Dystonia -- Cervical Dystonia -- Chapter 9: Botulinum Neurotoxin Injections for Cervical Dystonia -- Illustrations for Cervical Dystonia -- Upper Limb, Lower Limb, and Trunk Dystonia -- Chapter 10: Botulinum Neurotoxin for the Treatment of Idiopathic Primary Focal Limb Dystonia -- Chapter 11: Botulinum Neurotoxin for Treatment of Muscle Overactivity Associated with Upper Motor Neuron Syndromes -- Chapter 12: Botulinum Neurotoxin for the Treatment of Trunk Dystonia/Camptocormia -- Chapter 13: Botulinum Neurotoxin Injections for the Treatment of Tremor -- Illustrations for Upper Limb, Lower Limb, and Trunk Dystonia -- Part II: Botulinum Neurotoxins for Neurosecretory Disorders -- Chapter 14: Botulinum Neurotoxin Therapy for Problematic Sialorrhea -- Condition -- Chapter 15: Botulinum Neurotoxin Therapy for Hyperhidrosis -- Condition -- Part III: Botulinum Neurotoxins for Urologic Disorders -- Chapter 16: Botulinum Neurotoxin for Urologic Conditions -- Condition -- Part IV: Botulinum Neurotoxins for Pain Conditions -- Chapter 17: Botulinum Neurotoxins for the Treatment of Headache -- Condition -- Treatment of Headache -- Toxin Dilution -- Illustrations for Migraine Injection Patterns -- Chapter 18: Botulinum Neurotoxin for Musculoskeletal Pain Conditions -- Condition -- Myofascial Pain/Trigger Points -- Piriformis Syndrome -- Plantar Fasciitis -- Osteoarticular Pain Syndromes -- Shoulder and Ankle Joints -- BoNT Injections for Axial Skeletal Joints.

Anterior Knee Pain Associated with Patellar Maltracking -- Lateral "Epicondylitis" (or Epicondylosis) -- Other Musculoskeletal Pain Syndromes -- Thoracic Outlet Syndrome -- Musculoskeletal Pain Associated with Upper Motor Neuron Syndromes (UMNS) -- Appendices -- A. Ashworth and Modified Ashworth Scale for Grading Muscle Hypertonia -- B. Blepharospasm Disability Index Scale -- C. Blepharospasm Disability Scale -- D. Burke-Fahn-Marsden Dystonia Scale -- E. Dystonia Discomfort Scale -- F. Modified Tardieu Scale -- G. Toronto Western Spasmodic Torticollis Severity Scale -- References -- Index.
Abstract:
The Essential Guide for Clinicians Who Prescribe and Inject BoNTs. This is a detailed and practical guide to botulinum neurotoxin therapy (BoNT) and the wide range of applications for neurological and pain disorders. A unique reference source for new injectors and experienced clinicians alike, this indispensable manual provides information on dose, dilution, and indications for all four FDA-approved toxins in one handy text. Following a brief review of relevant pharmacology, the book provides product information and comparative distinctions between the four FDA-approved toxins (Botox , Myobloc , Xeomin , and Dysport ), along with indications and doses for FDA-approved conditions, guidance techniques, and common and emerging clinical applications. The heart of the book is an injection manual, organized anatomically and by condition and covering all applications for medical treatment. For each condition or site, information is provided on typical muscle pattern or muscle groups involved, dosing guidelines and dilution for the applicable toxins, number of injection sites, and potential risks and benefits. Targeting techniques are organized in table format for quick retrieval. Anatomic illustrations and cross-sections are provided to orient injectors and help identify optimal insertion points. An appendix with useful clinical rating scales is also included. Key Features: Presents state-of-the-art information about current indications for all four FDA-approved botulinum neurotoxins; Compares and contrasts the four toxins along with common and emerging clinical applications; Provides dosing guidelines for various indications and injection sites for each muscle; Includes anatomic drawings and cross-sections to illustrate muscle relationships and insertion points; Serves as a practical, portable, how-to guide for new and experienced clinicians.
Local Note:
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2017. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
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