Title Page -- Copyright Page -- Contents -- Contributors List -- Preface -- Video Clips Demonstrating Clinical Signs -- Section 1 Foundations of Clinical Neurology -- Chapter 1 Overview of Neuroanatomy -- Organization of the nervous system -- Development -- Organization of gray and white matter in the CNS -- Organization of gray and white matter in the PNS -- Gross anatomy of the CNS -- Topographic features of the spinal cord -- The peripheral nervous system -- Functional systems for clinicians -- Chapter 2 Cerebrospinal Fluid and the Blood-Brain Barrier -- Blood-brain barrier -- Cerebrospinal fluid -- References -- Chapter 3 Immunology of the Central Nervous System -- References -- Chapter 4 Pharmaceutical Considerations for Treatment of Central Nervous System Disease -- Introduction to neuropharmacology -- Antibacterial drugs -- Antiviral drugs -- Anti-inflammatory drugs -- Anticonvulsant drugs -- Drugs affecting behavior -- References -- Chapter 5 Fundamental Neurophysiology -- Ionic gradients and membrane potentials -- Action potentials -- The neuron -- The synapse -- Metabolic aspects of neuronal function -- Glia -- References -- Further Reading -- Section 2 Clinical Equine Neurology -- Chapter 6 Examination of the Nervous System -- Behavior, mental status, and coordination of the head -- Cranial nerves -- Skin, trunk, and cutaneous trunci reflexes -- Limb placement -- Gait analysis -- Recumbent patients -- Examination of foals -- Neurologic issues of the prepurchase examination -- Differentiating neurogenic and musculoskeletal gait abnormalities -- Examination of the peripheral nerves -- Neuroanatomic localization and case synthesis -- References -- Chapter 7 Differential Diagnosis and Management of Horses with Seizures or Alterations in Consciousness -- Management of horses with seizure disorders -- Narcolepsy -- References.

Chapter 8 Differential Diagnosis of Equine Spinal Ataxia -- References -- Chapter 9 Differential Diagnosis and Management of Cranial Nerve Abnormalities -- Head tilt and circling -- Temporohyoid osteoarthropathy -- Differential diagnosis and management of disorders of mastication and deglutition -- Blindness, anisocoria, and strabismus -- Horner's syndrome -- Facial paralysis -- References -- Chapter 10 Sleep and Sleep Disorders in Horses -- Confusion regarding equine sleep -- Human sleep -- Sleep in horses -- Environmental sleep influences -- Disorders of sleep -- References -- Chapter 11 Headshaking -- Signalment -- Clinical signs -- Etiopathogenesis -- Anatomy -- Diagnosis -- Treatment -- References -- Chapter 12 Differential Diagnosis of Urinary Incontinence and Cauda Equina Syndrome -- Urinary incontinence in horses -- Cauda equina syndrome -- References -- Chapter 13 Differential Diagnosis of Muscle Tremor and Paresis -- Differentials for diffuse neuromuscular disease -- Differentials for focal neuromuscular disease -- References -- Chapter 14 Electrodiagnostic Evaluation of the Nervous System -- Electromyography -- Conduct of NCS -- Magnetic motor evoked potentials -- Sensory evoked potentials -- Electroencephalography -- References -- Chapter 15 Anesthetic Considerations for Horses with Neurologic Disorders -- Neurologic complications of general anesthesia -- Anesthesia for myelography -- Anesthesia for cervical surgery -- Anesthesia for head trauma or cranial mass -- Conclusions -- References -- Chapter 16 The Basics of Equine Neuropathology -- The pathologic examination of the nervous system -- Systemic neuropathology -- References -- Chapter 17 Diagnostic Imaging of the Equine Nervous System -- Radiography -- Ultrasound -- Magnetic resonance imaging/computed tomography -- References -- Section 3 Specific Disease Syndromes.

Chapter 18 Equid Herpesvirus-Associated Myeloencephalopathy -- History of equine herpesvirus myeloencephalopathy -- The virus -- Pathogenesis -- Clinical signs -- Diagnosis -- Therapeutic recommendations for horses with EHM -- Epidemiology -- Outbreak prevention and mitigation -- References -- Chapter 19 Mosquito-Borne Infections Affecting the Central Nervous System -- History and signalment -- Physical examination -- Ancillary testing -- Zoonotic potential and environmental control -- Equine alphaviruses -- Miscellaneous alphaviruses -- Flavivirus infections -- Miscellaneous flaviviruses -- References -- Chapter 20 Contagious Neurological Diseases -- Rabies -- Borna disease virus -- Hendra and Nipah viruses -- Miscellaneous central nervous system infections -- References -- Chapter 21 Bacterial Infections of the Central Nervous System -- Agents -- Pathophysiology -- Clinical signs -- Diagnosis -- Treatment -- References -- Chapter 22 Equine Protozoal Myeloencephalitis -- Biology of Sarcocystis neurona and Neospora hughesi -- Epidemiology -- Pathophysiology -- Clinical signs -- Diagnosis -- Treatment -- Prognosis -- Prevention -- References -- Chapter 23 Parasitic Infections of the Central Nervous System -- Organisms and clinical syndromes -- Diagnosis -- Treatment -- Other neuroinvasive parasites -- References -- Chapter 24 Miscellaneous Infections of the Central Nervous System -- Cryptococcus -- Amebic meningoencephalitis -- Mycotic encephalitis -- Neuroborreliosis -- References -- Chapter 25 Disorders Associated with Clostridial Neurotoxins: Botulism and Tetanus -- Tetanus -- Botulism -- Prognosis -- References -- Chapter 26 Neurodegenerative Disorders -- Equine degenerative myeloencephalopathy -- Equine motor neuron disease -- Equine grass sickness -- Cerebellar degeneration -- Cerebellar abiotrophy -- References.

Chapter 27 Equine Hepatic Encephalopathy -- Pathophysiology -- Causes -- Clinical signs -- Laboratory findings -- Pathologic findings -- Treatment -- Prognosis -- References -- Chapter 28 Cervical Vertebral Stenotic Myelopathy -- Introduction -- Types of CVSM -- Epidemiology -- Clinical examination -- Neuropathophysiology -- Differential diagnoses for spinal ataxia -- Diagnostic techniques -- Postmortem examination and histopathology -- Treatment -- Prognosis -- Pathogenesis -- Conclusion -- References -- Chapter 29 Electrolyte Abnormalities and Neurologic Dysfunction in Horses -- The cell membrane potential -- Sodium -- Potassium -- Calcium -- Magnesium -- Phosphate -- References -- Chapter 30 Cervical Articular Process Disease, Fractures, and Other Axial Skeletal Disorders -- Anatomy of the articular process joints -- Pathological changes within APJs -- Neuropathophysiology -- Clinical presentation of cervical APJ disease -- Other axial skeletal disorders -- References -- Chapter 31 Congenital Malformation of the Nervous System -- Brain -- The spine and spinal cord -- References -- Chapter 32 Central Nervous System Trauma -- Etiology -- Pathophysiology -- Clinical signs and diagnostics -- Neurocritical care: acute treatment and monitoring -- Repairing the CNS: regeneration and rehabilitation -- Prognosis -- References -- Chapter 33 Disorders of the Peripheral Nervous System -- General treatment -- Specific peripheral nerve syndromes -- References -- Chapter 34 Equine Neurotoxic Agents and Conditions -- Pharmaceutical toxicity -- Environmental toxins -- Plant-and forage-associated intoxications -- References -- Chapter 35 Neonatal Encephalopathy and Related Conditions -- Incidence/occurrence -- Etiology and pathophysiology -- Clinical signs -- Clinicopathologic findings -- Treatment and prognosis -- References.

Chapter 36 Miscellaneous Movement Disorders -- Equine reflex hypertonia (plant associated stringhalt and sporadic stringhalt) -- Scandinavian knuckling horses -- Shivering (shivers) -- Stiff-horse syndrome -- Fibrotic myopathy -- References -- Chapter 37 Stereotypic and Behavior Disorders -- Weaving -- Stall walking -- Stall kicking -- Pawing -- Headshaking -- Self-mutilation -- Crib-biting and wind sucking -- Wood-chewing -- Aggressive behavior -- References -- Chapter 38 Miscellaneous Conditions -- Cholesterol granuloma -- Intracarotid injection -- Air embolism -- Spinal hematoma -- Uremic encephalopathy -- References -- Index -- EULA.