Heart Transplantation: Indications and Contradictions, Procedures and Complications -- Contents -- Preface -- Management of Tricuspid Regurgitation After Cardiac Transplantation -- Abstract -- Introduction -- Pathophysiology of Tricuspid Valve Regurgitation Following Cardiac Transplantation -- Management of Refractory Tricuspid Regurgitation -- Recent Experience with Repairs and Replacements -- Repair or Replacement? -- Preventing Post-Transplant TR -- Conclusion -- References -- Virtual Histology Intravascular Ultrasound in Coronary Allograft Vasculopathy -- References -- Gene Therapy for Prevention of Acute and Chronic Cardiac Rejection -- Abstract -- 1. Introduction -- 2. Antisense Cyclin-Dependent Kinase (cdk) 2 Kinase ODN -- 3. Antisense Proliferating-Cell Nuclear Antigen (PCNA) ODN -- 4. Antisense Bcl-x ODN -- 5. E2F Decoy -- 6. NF-kB Decoy -- 7. Summary -- Acknowledgement -- References -- Prevention of Heart Allograft Rejection by Immunotherapy with Ex Vivo-Expanded Foxp3+CD4+CD25+ Natural Regulatory T Cells -- Abstract -- Introduction -- Overview of Foxp3+CD4+CD25+ nTreg Cells -- Foxp3+CD4+CD25+ Treg Cells and Allograft Rejection -- Foxp3+CD4+CD25+ Treg Cells and Allograft Tolerance -- Rationale for Immunotherapy with Foxp3+CD4+CD25+ nTreg Cells -- Strategies and Procedures for Ex Vivo Expansion of CD4+CD25+ nTreg Cells -- Dynamics of Foxp3 Expression during Ex Vivo Expansion -- Suppressive Activity in MLR Assays -- Engraftment, Trafficking and Homing after Adoptive Transfer -- In Vivo Suppression and Allograft Survival -- Determinants of in Vivo Therapeutic Efficacy -- Issues Regarding CD8+CD25+ nTreg Cells -- Generation and Application of Foxp3+CD4+CD25+ iTreg Cells -- Challenges to Clinical Application -- Conclusion -- References -- Addressing the Shortage of Donor Cardiac Allografts - Use of Marginal Grafts -- Abstract.

Introduction -- Strategies to Improve Donor Organ Utilization -- Expanding the Use of Marginal Donor Organs -- Use of Marginal Cardiac Allografts for Heterotopic Transplantation -- Use of Long Ischemic Time Organs as Marginal Allografts -- Primary Graft Failure as a Consequence of Marginal Graft Use -- Older Donors and Cardiac Arrest Donors -- Continuous Perfusion of Donor Organs -- Conclusion -- References -- Dendritic Cell Modulation for Therapeutic Immunoregulation in Heart Transplantation -- Abstract -- Introduction -- Direct and Indirect Allorecognition -- Dendritic Cell Subsets and Dendritic Cell Maturation in Organ Transplantation -- Circulating Dendritic Cells in Human Organ Transplantation -- Therapeutic Strategies Based on Genetically Modified Dendritic Cells -- Therapeutic Modulation of Dendritic Cell Chemoattraction -- Generation of Regulatory Dendritics Cells -- Pharmacological Dendritic Cell Inhibitors -- Concluding Remarks -- Acknowledgements -- References -- Heart Transplantation: Indications and Contraindications, Procedures and Complications -- Abstract -- Introduction -- Epidemiology -- Pathogenesis of Bone Disease in Heart Transplant Candidates and Recipients -- Prevention and Treatment -- Conclusion -- Achnowledgement -- References -- The Role of Statins in Heart Transplantation -- Abstract -- Introduction -- Transplant Coronary Artery Disease: Pathogenesis and Pathomechanisms -- Treatment of Transplant Coronary Artery Disease: The Role of Statins -- Conclusion -- References -- Heart Transplantation from Non-Heart-Beating Donors -- Future Transplantation -- Abstract -- Introduction -- Donor Selection -- Resuscitation System -- Reperfusion Technique -- Evaluation of Post-Resuscitated (Pre-Tranaspalnt) Cardiac Function -- Preliminary Experimental Study for Clinical Application -- Material and Methods -- Results.

Discussion -- Conclusion -- Limitation of Our Study and Perspectives -- Second Experimental Study -- Material and Methods -- Results -- Conclusion -- Future Clinical Trial for Heart Transplantation from NHBDs -- Acknowledgements for All Coworkers -- References -- An Innovative Treatment for Cardiac Failure: Autologous Stem Cell Transplantation -- Abstract -- 1. Introduction -- 2. Cell Therapies in Heart Ischemia -- 3. Stem Cells -- 4. Human Adult Skeletal Muscle Stem Cells -- Conclusion -- References -- Continuous, Normothermic Heart Preservation in a Modified Langendorff Perfusion System - Ultrastructural Findings and Functional Morphology in a Pig Model -- Abstract -- Introduction -- Results -- Electronmicroscopy -- Conclusion -- Acknowledgements -- References -- Surgical Alternatives to Heart Transplantation -- Abstract -- Introduction -- Revascularization for Ischemic Cardiomyopathy -- Mitral Regurgitation in Cardiomyopathy and the Role of Surgical Intervention -- Surgical Placement of Permanent Left Ventricular Pacing Leads -- Surgical Treatment of Left Ventricular Aneurysm -- Other Surgical Options for Cardiomyopathy -- Mechanical Circulatory Support for the Failing Heart -- Conclusion -- References -- Index.