THE RIBONUCLEOTIDEREDUCTASE FAMILY:GENETICS AND GENOMICS -- Contents -- Preface -- Introduction -- RNR Classification and Occurrence -- Class I RNRs -- Class II RNRs -- Class III RNRs -- RNR distribution as seen in RNRdb -Ribonucleotide Reductase Database -- Atypical and Unconventional RNRs -- RNR Diversification -- Modularity Hypothesis for RNR ClassDiversificatio -- Regulation of RNRs -- Archaea -- Eubacteria -- Mutational Studies in RNRs -- RNR as an Antiproliferative Targetfor Disease Control -- Substrate Analogues -- Radical Scavengers Attacking the TyrosylRadical -- Iron Chelators -- Peptidomimetics Corresponding to the CTerminusof NrdB -- Manipulating the Expression of RNR -- Other Potential Inhibitors and AllostericNucleotide Analogues -- Future Antiproliferative Regimes -- Acknowledgments -- References -- Index.