PIONEERING HUMAN MYOBLASTGENOME THERAPY -- CONTENTS -- PREFACE -- INTRODUCTION -- DEVELOPMENT OF MAMMALIAN SKELETAL MUSCLES -- Myoblasts -- Natural Cell Fusion -- Myotubes -- Myotube Maturation -- Broad Perspective -- DUCHENNE MUSCULAR DYSTROPHY -- Murine Dystrophy Etiology-General Membrane Defect -- MUSCLE TRANSPLANTATION AND REGENERATION -- Normal Regenerates -- Satellite Cells -- Dystrophic Regenerates -- GENE TRANSFER -- Dystrophyc Genes -- Dystrophin -- Dystrophin Up-Regulation -- Plasmid Injection -- Transfected Myoblast Transfer -- Dystrophin-Associated Glycoproteins (DAGs) -- Perspectives -- Myoblast Transfer -- What is MTT or HMGT? -- How MTT/HMGT Works? -- Origin of MTT/HMGT -- Neural Hypothesis of Muscular Dystrophy -- Animal Models -- Cell Therapy VS Gene Therapy -- Development of MTT/HMGT -- MYOBLAST TRANSFER IMPROVES MUSCLEGENETICS/BIOCHEMISTRY/STRUCTURE/FUNCTIONAND NORMALIZES THE BEHAVIOR AND LIFE SPAN OFDYSTROPHIC MICE -- Genetic Improvement -- Biochemical Improvement -- Structural Improvement -- Functional Improvement -- Behavioral Improvement -- Life Prolongation -- Perspectives -- MYOBLAST TRANSFER IN DMD SUBJECTS -- SINGLE MUSCLE TREATMENT -- SUBJECTS AND METHODS -- Approval -- Subjects -- Muscle Preparation -- Donor Myoblasts -- Myoblast Transfer -- Immunosuppression -- Effect of Cy on Myoblasts -- Functional Monitor -- Structural Monitor -- Biochemical Monitor -- RESULTS -- Myoblast Culture -- Functional Improvement -- Structural Improvement -- Biochemical Improvement -- Clinical Tests -- DISCUSSION -- LOWER BODY TREATMENT -- BETTER REPAIR THAN REPLENISH -- FROZEN OR FRESH -- CYCLOSPORINE -- DOSING OF CELLS -- CONTROVERSIES -- WHOLE BODY TREATMENT -- Dose Escalation -- HUMAN MYOBLAST GENOME THERAPYAND THE REGENERATIVE HEART -- HEART MUSCLE REGENERATION -- NATURAL HEART MUSCLE REPAIR -- MYOCARDIAL CELL TRANSPLANTATION.

CHOISE OF CELL -- MYOBLAST SUITABILITY -- WORLD'S FIRST HUMAN MYOBLAST TRANSFER INTOTHE HEART -- THE REGENERATIVE HEART -- PROOF OF CONCEPT -- THERAPEUTIC ANGIOGENESIS -- VEGF165PROTEIN DELIVERY -- ANGIOMYOGENESIS -- FIRST IN MAN (FIM) STUDIES -- Myoblast Autograft -- Myoblast Allograft -- THE WORLD'S FIRST MYOBLAST STUDYOF TYPE II DIABETIC PATIENTS -- FUTURE PERSPECTIVES -- ESSENCE OF CELL THERAPY -- HEART MUSCLE GENES -- THE ULTIMATE GENE TRANSFER -- CONTROLLED CELL FUSION -- ANTI-AGING COSMETIC ENHANCEMENT -- BONE DEGENERATION -- MYOBLAST: THE UNIVERSAL GENE TRANSFERVEHICLES -- AUTOMATED CELL PROCESSORS -- CELL THERAPY IS NOW -- REFERENCES -- INDEX.