PHARMACOLOGICAL INTERVENTION IN MANAGEMENT OF NECK PAIN DISORDERS: A REVIEW -- PHARMACOLOGICAL INTERVENTION IN MANAGEMENT OF NECK PAIN DISORDERS: A REVIEW -- Library of Congress Cataloging-in-Publication Data -- Contents -- Preface -- Chapter I Introduction -- Chapter II Pain Perception -- Acute vs Chronic Pain -- Mediators of Pain Perception -- Central Mediators -- Peripheral Mediators -- Neuropeptides -- Substance P -- Calcitonin Gene Related Peptide (CGRP) -- Tachykinins -- Galanin -- Vasoactive Intestinal Peptide (VIP) -- Somatosstatin -- Endogenous Opioids -- Endogenous Cannobinoids -- Nociceptin/Orphanin FQ (N/OFQ) -- Glutamate -- Inhibitory Amino Acids -- Monoamines -- Free Radicals -- Purines -- Bradykinin -- Histamine -- Cytokines (Interleukins, Interferon, and Tumor Necrosis Factor) -- Nerve Growth Factor (NGF) -- Eicosanoids -- Lipoxins -- Resolvins and Protectins -- Ions Channel Ligands -- Chapter III Central, Topical and Peripherally Acting Analgesics -- A. Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) -- Classification of COX Inhibitors (Tables 1 and 2) -- Topical NSAIDs -- B. Acetaminophen -- The Para-Amino Phenol Derivative -- C. Opioids -- Transdermal Fentanyl -- Opioid and Dependence -- D.Capsaicinoids and Vanilloids Agonists -- Capsaicin -- Homocapsaicin -- Resiniferatoxin -- E. Neurotoxins -- Botulinum Toxin -- F. Alpha-2 Adrenoceptor Agonists -- Tizanidine -- Clonidine -- G. NMDA- Receptor Antagonists -- Dextromethorphan -- Amantadine -- Memantine -- Ketamine -- H. Muscle Relaxants -- Baclofen -- Cyclobenzaprine -- I. Biological Drugs -- Etanercept -- 2. Interleukin-1 (IL-1) Blockers e.g. Anakinara -- 3. Interleukin-1 (IL-1) Trap e.g. Rilonacept -- J. Adenosine -- K. Cholinergic Drugs -- L. Cannabinoids -- M. Non-Patch Type Topical Pain Relievers -- Ketamine -- Amitriptyline -- Doxepin -- N. Spinal Injections.

Facet Joint Injection -- Selective Nerve Block, Transforaminal Epidural Injection -- Intrathecal Pump -- Sympathetic or Somatic Nerve Block -- Corticoteroids -- Local Anaesthetics (Bupivacaine, Lidocaine) -- 2 Adrenoceptor Agonists -- Ziconotide -- Baclofen -- Intrathecal Cocktails -- Chapter IV Antimicrobials -- Discitis -- Pyogenic Osteomyleitis of the Cervical Spine -- Epidural Abscess -- Chapter V Complementary/Alternative Analgesia -- Acupuncture -- Trigger Points -- Mind-Body Therapy -- Magnet Therapy -- Prolotherapy or Proliferative Injection Therapy or Regenerative Injection Therapy -- Exercise -- Spinal Manipulation -- Nutraceuticals -- Glucosamine -- Chondroitin Sulfate -- Methylsulfonylmethane -- Avocado-Soybean Unsaponifiables -- Omega-3- Fatty Acids -- S-Adenosyl Methionine -- Herbal Medicines -- Cayenne (Capsicum Frutescens) -- St John's Wort (Hypericum Perforatum) -- Siberian Gingseng -- Tumeric -- Calendula Officinalis (Also Known as Marigold) -- Devil's Claw Root (Harpagophytum Procumbens) -- Willow Bark (Salix Alba) -- Feverfew (Tanacetum Parthenium) Sometimes Called a "Summer Daisy -- Dong Quai (Radix Angelicae sinesis) -- Licorice (Glycyrrhiza Glabra) Root -- Dandelion (Taraxacum Officinale) -- Ginger (Zingiber Officinale) Tea -- Pomegrante( Punica Granatum L.) -- Gamma-Linolenic Acid (GLA)-Containing Herbs -- Ayurvedic preparation -- Chapter VI Quality of Life -- Conclusion -- References -- Index.