NEURAL TUBE DEFECTS -- NEURAL TUBE DEFECTS -- Contents -- Preface -- Prevalence, Pathogenesisand Prevention of Neural Tube Defects -- Abstract -- 1. Prevalence of Neural Tube Defects (NTDs) -- 2. Prevention of NTDs -- 3. Pathogenesis of NTDs -- References -- Primary Prevention of Neural Tube Defects: Not Only Preconception Folic Acid Supplementation -- Abstract -- Introduction -- Previous Pregnancy with NDT -- Hyperomocisteinemia and Polymorphisms Associated with NTDs -- Maternal Intake of Micronutrients -- Pregestational Diabetes -- Maternal Obesity -- Smoke -- Drugs -- Hyperthermia -- Parental Occupational Exposure and other Chemical Agents -- Conclusion -- References -- Understanding and Preventing Folic Acid-Resistant Neural Tube Defects -- Abstract -- Introduction -- Folic Acid and NTDs -- Folate Supplementation -- Classification of NTDs -- Inositol and NTDs -- Safety of Inositol -- Inositol and Caffeine Intake -- References -- Folic Acid, Homocysteine and Neural-Tube Defects -- Abstract -- Introduction -- Folic Acid and Homocysteine Roles during Embryonic Development -- Effects of FA and Hcy on Development ofthe Chick Embryo Central Nervous System -- Conclusion -- References -- Developmental Delay in Interneuron, Motor Neuron, Sensory Tract, and Synapse Formation in Chick Spina Bifida -- Abstract -- 1. Introduction -- 2. Material and Methods -- 3. Result -- (1) Locomotory Behavior of SBA Hatchlings -- (2) Histological Observations of Spinal Neurons in the Lesioned Segment -- (3) Developmental Motor Neuron Delay in SBA Chicks -- (4) Tracing of the Sensory Tract -- (5) Morphometric Analysis of the Extracellular Space and Synapses by Large Montage Electron Microscopy -- Conclusion -- Ackowledgments -- References -- Do Neural Tube Defects Lead to Structural Alterations in the Urinary and Genital Organs in Human Fetuses? -- Abstract.

Introduction -- Methods -- Structure of the Urogenital Organs -- Ureter -- Bladder -- Penis and Urethra -- Comments -- Conclusion -- References -- Index.