Contents -- 1 Adherence -- Introduction -- Adherence measures -- Strategies to improve adherence -- Adherence counseling -- 2 Adverse drug reactions and drug interactions -- Introduction -- Classification of ADRs -- Adverse reactions: drug or disease? -- Helping patients understand the risk of ADRs -- Reporting ADRs -- Drug interactions -- Managing drug interactions -- 3 Anaphylaxis -- Symptoms and signs of anaphylaxis -- Treatment of anaphylaxis -- Prevention of anaphylaxis -- 4 Clinical pharmacy skills -- Clinical pharmacy definition -- Prescription screening and monitoring -- Pharmacist documentation in patient medical records (PMR) -- Understanding medical records -- Medication review -- Medication reconciliation -- Intervention monitoring -- Obtaining patient medication histories -- Medication-use evaluation (MUE) -- Medication errors -- Financial reports and budget statements -- Hospital budget statements -- Patient assistance programs -- Drug and medication information services -- 5 Tips for professional conduct -- Communication skills -- Oral presentation skills -- Written communication skills -- Assertiveness -- Leading meetings -- Prioritizing -- Project planning -- Time management -- Ethical dilemmas -- Working with medical staff -- Patient etiquette -- Working with distressed patients -- Working with dying patients -- 6 Pharmacy automation -- Pharmacy automation and technology -- Computerized prescriber order entry (CPOE) and clinical decision support (CDS) -- Automated storage and distribution systems -- Bar-coded medication administration -- Computerized infusion pumps ("smart pumps") -- 7 Clinical trials -- Phases of clinical trials -- Licensing -- U.S. Food and Drug Administration -- ASHP Guidelines on Clinical Drug Research -- Institutional review boards (IRBs) -- Pharmacists advising IRBs -- Gene therapy.

8 Evidence-based medicine -- Evidence-based medicine (EBM) and clinical pharmacy -- Statistical vs. clinical significance -- Odds ratios and relative risk -- Types of data -- Descriptive statistics -- Mean difference and the standardized mean difference -- L'Abbé plots -- Assessing the quality of randomized studies -- Critical appraisal of systematic reviews -- Critical assessment of papers -- Useful references for pharmacists -- The number needed to treat (NNT) and number needed to harm (NNH) -- Confidence intervals -- Validity -- 9 Herbal medications -- Overview of herbal medications -- Legislation of herbal medications -- Herbal medications of current interest -- Safety and adverse effects -- Drug interactions -- Special considerations -- 10 Patient management issues -- Introduction to liver disease -- Drug use in liver disease -- Drug dosing in liver disease -- Hepatorenal syndrome -- Drugs in renal impairment -- Drugs in pregnancy -- Drugs in breastfeeding -- Medicines for children: introduction -- Medicines for children: pharmacodynamics and pharmacokinetics -- Medicines for children: licensing -- Medicines for children: calculating children's doses -- Medicines for children: adherence -- Medicines for elderly people: introduction -- Medicines for elderly people: pharmacokinetics and pharmacodynamics -- Medicines for elderly people: medication review -- Glucose 6-phosphate dehydrogenase (G6PD) deficiency -- Drug use in celiac disease -- Drug use in acute porphyria -- Drug and food allergies -- Drug therapy for enteral feeding tubes -- Patients with altered GI tracts and bariatric surgery -- Pharmacogenomics -- Transdermal drug therapy -- Contrast media -- Principles of extravasation -- Vesicant potential of chemotherapeutic agents -- Management of extravasations in adult patients -- Treatment of extravasations in adult patients.

11 Pharmaceutical calculations -- Concentrations -- Moles and millimoles -- Milliequivalents and milliosmoles -- Practical issues involving pharmaceutical calculations -- Pharmaceutical calculations involving infusion rates -- 12 Pharmaceutical and patient-centered care -- The concepts of patient-centered and pharmaceutical care -- Core elements of pharmaceutical care -- Medication problem checklist -- Pharmaceutical care economics -- Standards for research -- Future practice goals -- Pharmacy workforce -- Medication therapy management -- 13 Medication management -- Medication management -- Evaluating new drugs -- How to write a protocol -- U.S. drug approval process -- Pharmacy and therapeutics committees -- Clinical pathways and collaborative practice arrangements -- Electronic prescribing -- Incident reporting -- Pharmaceutical sales representatives -- Confidentiality -- Conflicts of interest -- Disposal of medicines -- 14 Research -- Audit and research -- Writing a research proposal -- Reference management software -- Preparation of materials for publication -- 15 Therapy-related issues -- Allergic rhinitis -- Dermatological drug reactions -- Drug desensitization -- Rheumatoid arthritis -- Systemic lupus erythematosus and other collagen-vascular diseases -- Angina -- Unstable angina and non-ST elevation myocardial infarction -- ST-elevation myocardial infaction -- Tolerance to nitrate therapy -- Acute decompensated heart failure -- Chronic heart failure -- Acute cardiogenic pulmonary edema -- Cardiopulmonary resuscitation in adults -- Hypertension -- Understanding anticoagulation -- Clinical use of anticoagulants -- Warfarin dosing -- Counseling patients treated with warfarin -- Outpatient anticoagulation management -- Hyperlipidemia -- Introduction to critical care -- Acid-base disorders -- Mechanical ventilation -- Motility stimulants.

Renal-replacement therapy -- Sedation, paralysis, delirium -- Stress-ulcer prophylaxis -- Vasoactive drugs -- Wound care -- Management of calcium imbalance -- Management of magnesium imbalance -- Management of phosphate imbalance -- Management of potassium imbalance -- Management of sodium imbalance -- Prescribing intravenous fluids -- Fluid balance -- Practical issues concerning parenteral nutrition -- Normal nutritional requirements -- Nutritional support in adults -- Children's parenteral nutrition regimens -- Enteral feeding -- Intravenous therapy at home -- Sodium content of parenteral drugs -- Diabetes mellitus -- Blood glucose monitoring and control -- Contraception -- Menopause -- Obesity -- Osteoporosis -- Thyroid disorders -- Constipation in adults -- Diarrhea -- Gastroesophageal reflux disease -- Helicobacter pylori infections -- Hepatic encephalopathy -- Hepatitis -- Inflammatory bowel disease -- Management of nausea and vomiting -- Basic microbiology -- Modes of action of antimicrobials -- Selection and use of antimicrobials -- Antimicrobial prophylaxis -- Optimizing antimicrobial use -- Antimicrobial resistance -- Infection control -- Human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) -- Opportunistic infections-HIV/AIDS -- HIV post-exposure prophylaxis (PEP) -- Vaccine overview -- Vaccines for pediatrics -- Vaccines for adults -- Alzheimer's disease -- Headaches -- Multiple sclerosis -- Myasthenia gravis -- Parkinson's disease -- Seizure disorder -- Stroke -- Policy for administration and handling of cytotoxic drugs -- Clinical screening of chemotherapy prescriptions -- Chemotherapy dosing -- Intrathecal administration of chemotherapy -- Supportive care: anemia -- Antiemetics for prophylaxis of chemotherapy-induced nausea and vomiting -- Febrile neutropenia -- Hypercalcemia -- Tumor lysis syndrome.

Pain: a definition -- Assessment of pain -- Acute pain -- Chronic pain -- Cancer pain -- Neuropathic pain -- Osteoarthritis -- Equianalgesic dosing of opioids -- Compatibility of drugs in pain and palliative care -- General psychiatry -- Anxiety disorders -- Depression -- Counseling on antidepressants -- Schizophrenia -- Managing antipsychotic side effects -- Bipolar disorder -- Monitoring of mood stabilizers -- Long-term asthma management in adults -- Inhaler techniques -- Chronic obstructive pulmonary disease -- Cystic fibrosis -- Acute respiratory distress syndrome -- Respiratory syncytial virus -- Tobacco cessation -- Solid organ transplantation -- Management of poisoning inquiries -- Treatment of alcohol withdrawal -- Treatment of selected overdoses -- Acetaminophen -- Anticholinergics -- Benzodiazepines -- Beta-adrenergic blockers -- Calcium channel blockers -- Cardiac glycosides -- Cyanide -- Cyclic antidepressants -- Narcotic analgesics -- Toxic alcohols/glycols-ethylene glycol -- Toxic alcohols/glycols-methanol -- Appendix -- Pathology ranges and interpretation -- Normal ranges -- Pediatric normal laboratory values -- Drug interference with laboratory tests -- Therapeutic drug monitoring (TDM) in adults -- Useful Web sites -- Levels of evidence-based medicine -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- X -- Y -- Z.