INFECTIOUS DISEASES IN AN AGE OF CHANGE -- Copyright -- Preface -- REFERENCES -- Acknowledgments -- Contents -- Lyme Disease: A Growing Threat to Urban Populations -- VECTOR AND ANIMAL HOSTS -- EVOLUTION OF ENVIRONMENT -- EPIDEMIOLOGY OF LYME DISEASE -- CLINICAL PICTURE -- CHRONIC FATIGUE OR FIBROMYALGIA FOLLOWING LYME DISEASE -- MISDIAGNOSIS OF CHRONIC LYME DISEASE -- DIAGNOSTIC TESTS -- TREATMENT -- PREVENTION -- SUMMARY -- REFERENCES -- Working Parents: The Impact of Day Care and Breast-Feeding on Cytomegalovirus Infections in Offspring -- THE PROBLEM -- ROLE OF BREAST-FEEDING -- IMPORTANCE OF DAY-CARE CENTERS -- COMBINED EFFECT OF BREAST-FEEDING AND DAY-CARE CENTERS -- RISK TO CARE GIVERS -- CONCLUSIONS -- SUMMARY -- REFERENCES -- Changes in Human Ecology and Behavior in Relation to the Emergence of Diarrheal Diseases, Including... -- DEVELOPING WORLD ECOLOGY -- INDUSTRIALIZED WORLD ECOLOGY -- CHANGES IN HUMAN BEHAVIOR AND ECOLOGY THAT PROMOTE THE EMERGENCE AND/OR AMPLIFIED TRANSMISSION OF EN... -- Developing Areas -- Industrialized Areas -- CHANGES IN THE EPIDEMIOLOGIC BEHAVIOR OF CHOLERA,IN PART DUE TO CHANGES IN HUMAN BEHAVIOR -- CONCLUSIONS -- SUMMARY -- REFERENCES -- Dengue: The Risk to Developed and Developing Countries -- TRANSMISSION CYCLE, DISEASE, AND PATHOGENESIS -- HISTORY OF EPIDEMICS AND THE EMERGENCE OF DHF/DSS -- DENGUE IN THE DEVELOPED WORLD -- ECOLOGIC BASIS FOR THE EMERGENCE OF DENGUE -- INTRODUCTION AND SPREAD OF A SECOND DENGUE VECTOR IN THE AMERICAS -- MOLECULAR EPIDEMIOLOGY AND VIRUS VARIATION -- Use of Dengue Genetic Analysis to Explain the Emergence of Dengue in Africa -- Molecular and Biological Evidence for Variation in Dengue Virulence -- FLAVIVIRUS AND DENGUE EVOLUTION:A BIOLOGICAL PERSPECTIVE AND SOME SPECULATIONSON FUTURE CHANGES IN... -- PREVENTION AND CONTROL -- SUMMARY -- REFERENCES.

Hepatitis Viruses: Changing Patterns of Human Disease -- HEPATITIS A VIRUS -- History -- Epidemiology -- Virology -- Clinical Characteristics -- Changing Patterns -- HEPATITIS B VIRUS -- History -- Epidemiology -- Virology -- Clinical -- Changing Patterns -- HEPATITIS C VIRUS -- History -- Epidemiology -- Virology -- Clinical Characteristics -- Changing Patterns -- HEPATITIS D VIRUS -- History -- Epidemiology -- Virology -- Clinical Characteristics -- Changing Patterns -- HEPATITIS E VIRUS -- History -- Epidemiology -- Virology -- Clinical Characteristics -- Changing Patterns -- INTERACTIONS OF THE HEPATITIS VIRUSES -- OTHER HEAPTITIS VIRUSES -- CONCLUSIONS -- SUMMARY -- REFERENCES -- Population Migration and the Spread of Types 1 and 2 Human Immunodeficiency Viruses -- MIGRATION OF POPULATIONS: DEFINITIONS -- AFRICA -- THE EFFECT ON DEMOGRAPHICS -- HIV-2 AND WEST AFRICA -- SPREAD OF HIV-2 OUTSIDE OF WEST AFRICA -- HIV-1 IN THE AMERICAS -- HIV INFECTION IN SOUTHEAST ASIA -- LEGAL RESTRICTIONS -- CONCLUSIONS -- SUMMARY -- REFERENCES -- Impact of Malaria on Genetic Polymorphism and Genetic Diseases in Africans and African Americans -- ESTIMATES OF MORTALITY FROM MALARIA -- HYPERTENSION AND IRON OVERLOAD -- HLA AND MALARIA -- BLOOD GROUPS AND MALARIA -- SUMMARY -- REFERENCES -- Hospital-Acquired Infections: Diseases with Increasingly Limited Therapies -- CHANGING FEATURES OF THE POPULATIONOF HOSPITALIZED PATIENTS -- CHANGES IN TYPES OF PROCEDURES PERFORMED FOR COMPLEX ILLNESSES -- CHANGING SPECTRUM OF NOSOCOMIAL PATHOGENS EARLY IN THE ANTIMICROBIAL ERA -- PROBLEMS OF ANTIMICROBIAL RESISTANCE IN SELECTED NOSOCOMIAL PATHOGENS -- S. aureus -- CNS -- CHANGES IN ANTIMICROBIAL USAGE OVER THE PAST TWO DECADES -- THE INCREASING PROBLEM OF ANTIBIOTIC RESISTANCE IN ENTEROCOCCUS SPP.

RESISTANCE TO THIRD-GENERATION CEPHALOSPORINS AMONG GRAM-NEGATIVE AEROBIC BACILLI -- CONTROL OF NOSOCOMIAL INFECTIONS DUE TO RESISTANT BACTERIA -- SUMMARY -- REFERENCES -- Evolution of Drug-Resistant Tuberculosis:A Tale of Two Species -- SUMMARY -- REFERENCES -- Effect of Human Ecology and Behavior on Sexually Transmitted Diseases, Including HIV Infection -- CHANGING PATTERNS OF SEXUALLY TRANSMITTED DISEASES -- ENVIRONMENTAL CHANGES AFFECTING STD PATTERNS -- The Physiological Microenvironment -- The Behavioral Personal Environment -- The Sociocultural Macroenvironment -- IMPLICATIONS FOR EFFECTIVE STD PREVENTION PROGRAMS -- SUMMARY -- REFERENCES -- Genital Human Papillomavirus Infection -- RELATIONSHIP BETWEEN HPV INFECTIONAND CERVICAL CANCER -- MANAGEMENT OF GENITAL HPV LESIONS -- PROSPECTS FOR VACCINATION -- SUMMARY -- REFERENCES -- Herpes Simplex Virus Infections of Women and Their Offspring: Implications for a Developed Society -- INCIDENCE OF NEWBORN INFECTION -- PATHOGENESIS OF NEONATAL HSV INFECTIONS -- EPIDEMIOLOGY OF MATERNAL HSV INFECTIONS -- MATERNAL GENITAL HERPES SIMPLEX INFECTIONS: CLINICAL AND VIROLOGIC PARAMETERS -- CLINICAL PRESENTATION -- Disseminated Infection -- Encephalitis -- Skin, Eye, and/or Mouth Infection -- TREATMENT OF NEONATAL HSV INFECTION -- COST-BENEFIT ANALYSES OF ANTIVIRAL THERAPY -- PREVENTION OF NEONATAL HSV INFECTION -- Antiviral Prophylaxis -- Immunoprophylaxis -- CONCLUSION -- SUMMARY -- REFERENCES -- Human Ecology and Behavior and Sexually Transmitted Bacterial Infections -- EPIDEMIOLOGIC MODELS OF STD -- GLOBAL HEALTH CARE AND THE DURATION OF INFECTIOUSNESS OF BACTERIAL STDS -- Developing Countries -- The United States -- TRENDS AND PATTERNS OF SEXUAL BEHAVIORS -- Developing Countries -- The United States -- DETERMINANTS OF EFFICIENCY OF TRANSMISSION OF STD.

ECOLOGIC FACTORS INFLUENCING THE EMERGENCE OF BACTERIAL STD -- Historical Stages of Economic Development -- Geography, Crowding, and Hygiene -- "Socio-Geographic Space" and Bacterial STDs -- War, Travel, and Migration -- The Demographic and Epidemiologic Transitions -- Ages of Sexual Maturation and of Marriage -- Social and Economic Development Policies in Developing Countries -- A ''Synergism of Plagues": STD/HIV, Teen Pregnancy, Violence, and Cocaine Use -- New Technology and Product Development -- ECOLOGIC AND BEHAVIORAL DETERMINANTS OF COMPLICATIONS AND SEQUELLAE OF BACTERIAL STDS -- POPULATIONAL VS. INDIVIDUAL DETERMINANTS OF STD RISK -- SUMMARY -- REFERENCES -- Vaccines for Bacterial Sexually Transmitted Infections: A Realistic Goal? -- CHANCROID -- SYPHILIS -- GONORRHEA -- Por as a Vaccine Candidate -- Pili as a Vaccine Candidate -- Other Possible Gonococcal Vaccines -- CHLAMYDIA -- Heat Shock Proteins and Hypersensitivity -- Momp as a Protective Antigen -- PROSPECTS FOR THE FUTURE -- SUMMARY -- REFERENCES -- Quest for Life-Long Protection by Vaccination -- THE IDEAL VACCINE -- PROTECTION THROUGH VACCINATION -- RESULTS WITH CURRENT VACCINES -- DISEASE ERADICATION THROUGH VACCINATION -- SUMMARY -- REFERENCES -- Index.