Contents -- 1. Introduction -- Host-Microbe Interactions: The Microbe Perspective -- 2. Is Metal Uptake Relatedto Ecological Niche inthe Vertebrate Host? -- 3. Competition for Metals among Microbes and Their Host -- 4. The Fate of Intracellular Metal Ions in Microbes -- 5. Common Mechanisms of Bacterial Metal Homeostasis -- 6. Intervention Strategies for Metal Defi ciency and Overload -- 7. Trace Metals in Host-Microbe Interactions -- Host-Microbe Interactions: The Host Perspective -- 8. Metal Homeostasis during Development, Maturation, and Aging -- 9. Impact of Metals on Immune Response and Tolerance, and Modulation of Metal Metabolism during Infection -- 10. Metal-Based Antiparasitic Therapeutics -- 11. Impact of Lifestyle on Metal Exposure, Homeostasis, and Associated Diseases -- 12. Obesity, Trace Metals, and Infection -- 13. Metals in Host-Microbe Interaction -- Metals in the Environmentas Risk Factors for Infectious Diseases -- 14. Selenium and Mercury -- 15. New Technologies Using Trace Metals of Concern -- 16. The Promise of Nanometals -- 17. Metals in the Environment as Risk Factors for Infectious Diseases -- Methods and Technologies for Analyzing Trace Metalsin Biological Systems -- 18. Emerging Strategies in Metalloproteo- mics -- 19. Measuring Metals in Complex Biological Systems -- 20. Methods and Technologies for Studying Metals in Biological Systems -- List of Acronyms -- Bibliography -- Subject Index.