
Metals in Medicine.
Title:
Metals in Medicine.
Author:
Dabrowiak, James C.
ISBN:
9781118681275
Personal Author:
Edition:
2nd ed.
Physical Description:
1 online resource (436 pages)
Contents:
Contents -- Title -- Copyright -- Dedication -- Feature Boxes -- Preface -- Acknowledgments -- 1 Inorganic Chemistry Basics -- 1.1 Crystal field theory -- 1.2 Molecular orbital theory -- 1.3 Absorption spectra of metal complexes -- 1.4 Magnetic properties of metal complexes -- 1.5 Reactions of metal complexes -- 2 Metallo-Drugs and Their Action -- 2.1 Introduction -- 2.2 Proteins as targets for metallo-drugs -- 2.3 DNA as a target for metallo-drugs -- 2.4 Reaction of metal complexes in the biological milieu -- 2.5 Evaluating the pharmacological effects of agents -- 2.6 From discovery to the marketplace -- 3 Cisplatin -- 3.1 Physical and chemical properties of cisplatin -- 3.2 Formulation, administration and pharmacokinetics -- 3.3 Reaction of cisplatin in biological media -- 3.4 Uptake, cytotoxicity and resistance -- 3.5 Interaction of cisplatin with cellular targets -- 4 Platinum Anticancer Drugs -- 4.1 Carboplatin -- 4.2 Oxaliplatin -- 4.3 New platinum agents -- 5 Ruthenium, Titanium and Gallium for Treating Cancer -- 5.1 Ruthenium compounds for treating cancer -- 5.2 Titanium compounds for treating cancer -- 5.3 Gallium for treating cancer -- 6 Gold Compounds for Treating Arthritis, Cancer and Other Diseases -- 6.1 Chemistry of gold in biological media -- 6.2 Gold compounds for treating arthritis -- 6.3 Gold complexes for treating cancer -- 6.4 Gold complexes for treating AIDS and other diseases -- 7 Vanadium, Copper and Zinc in Medicine -- 7.1 Vanadium for treating diabetes -- 7.2 Role of copper and other metal ions in Alzheimer's disease -- 7.3 Copper in Wilson's and Menkes diseases -- 7.4 Zinc-bicyclam: a chemokine receptor antagonist -- 8 Metal Complexes for Diagnosing Disease -- 8.1 Technetium in diagnostic nuclear medicine -- 8.2 Metal compounds as contrast agents for MRI -- 8.3 Radionuclides for palliative care and cancer treatment.
9 Nanomedicine -- 9.1 Nanoscience for treating disease -- 9.2 Nanomedicine in diagnosing disease -- 9.3 Potential health risks of nanoparticles -- Index.
Local Note:
Electronic reproduction. Ann Arbor, Michigan : ProQuest Ebook Central, 2017. Available via World Wide Web. Access may be limited to ProQuest Ebook Central affiliated libraries.
Genre:
Electronic Access:
Click to View