In vitro Neuromuscular Junction Induced from Human Induced Pluripotent Stem Cells
Title:
In vitro Neuromuscular Junction Induced from Human Induced Pluripotent Stem Cells
Author:
Lin, Chuang-Yu
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (361 seconds)
Series:
Developmental Biology
General Note:
Title from resource description page
Abstract:
Here we provide a protocol to generate in vitro NMJs from human induced pluripotent stem cells (iPSCs). This method can induce NMJs with mature morphology and function in 1 month in a single well. The resulting NMJs could potentially be used to model related diseases, to study pathological mechanisms or to screen drug compounds for therapy.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/61396