In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding
Title:
In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding
Author:
Fan, Chen
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (500 seconds)
Series:
Bioengineering
General Note:
Title from resource description page
Abstract:
This protocol describes the use of macromolecular crowding to create an in vitro human hypertrophic scar tissue model that resembles in vivo conditions. When cultivated in a crowded macromolecular environment, human skin fibroblasts exhibit phenotypes, biochemistry, physiology, and functional characteristics resembling scar tissue.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/61037