Intrathecal Delivery of Antisense Oligonucleotides in the Rat Central Nervous System
Title:
Intrathecal Delivery of Antisense Oligonucleotides in the Rat Central Nervous System
Author:
Chen, Yi
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (467 seconds)
Series:
Neuroscience
General Note:
Title from resource description page
Abstract:
Here, we describe a method for delivering drugs to the rat central nervous system by implanting a catheter into the lumbar intrathecal space of the spine. We focus on the delivery of antisense oligonucleotides, though this method is suitable for delivery of other therapeutic modalities as well.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/60274