Chronic Salmonella Infection Induced Intestinal Fibrosis
Title:
Chronic Salmonella Infection Induced Intestinal Fibrosis
Author:
Lo, Bernard C.
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (520 seconds)
Series:
Immunology and Infection
General Note:
Title from resource description page
Abstract:
This protocol describes a mouse model of Salmonella driven intestinal fibrosis that resembles key pathological hallmarks of Crohn's disease including transmural inflammation and fibrosis. This method can be used to evaluate host factors that alter fibrotic outcomes using mutant mice maintained on a C57Bl/6 genetic background.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/60068