An Advanced Murine Model for Nonalcoholic Steatohepatitis in Association with Type 2 Diabetes
Title:
An Advanced Murine Model for Nonalcoholic Steatohepatitis in Association with Type 2 Diabetes
Author:
Sbierski-Kind, Julia
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (617 seconds)
Series:
Immunology and Infection
General Note:
Title from resource description page
Abstract:
A simple and reliable diet-induced rodent animal model for nonalcoholic steatohepatitis (NASH) is described, achieved through non-SPF housing of the animals and administration of a specific high-fat diet. We describe identification of hepatic and adipose immune cell subsets to recapitulate human immunological conditions by exposing mice to environmental germs.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/59470