A GPC3-targeting Bispecific Antibody, GPC3-S-Fab, with Potent Cytotoxicity
Title:
A GPC3-targeting Bispecific Antibody, GPC3-S-Fab, with Potent Cytotoxicity
Author:
Wang, Yanlan
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (673 seconds)
Series:
Cancer Research
General Note:
Title from resource description page
Abstract:
Here, we present a protocol to produce a bispecific antibody GPC3-S-Fab in Escherichia coli. The purified GPC3-S-Fab has potent cytotoxicity against GPC3 positive liver cancer cells.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/57588