Fractionation for Resolution of Soluble and Insoluble Huntingtin Species
Title:
Fractionation for Resolution of Soluble and Insoluble Huntingtin Species
Author:
Ochaba, Joseph
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (428 seconds)
Series:
Biochemistry
General Note:
Title from resource description page
Abstract:
A method is described for fractionation of insoluble and soluble mutant huntingtin species from mouse brain and cell culture. The method described is useful for characterization and quantification of huntingtin protein flux and aids in analyzing protein homeostasis in disease pathogenesis and in the presence of perturbations
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/57082