A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries
Title:
A Platform of Anti-biofilm Assays Suited to the Exploration of Natural Compound Libraries
Author:
Skogman, Malena E.
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (579 seconds)
Series:
Immunology and Infection
General Note:
Title from resource description page
Abstract:
Biofilm infections show high tolerance towards chemotherapy. No single assay captures the complexity of biofilms. Instead, complementary assays are needed. We present a screening platform (developed for S. aureus) that combines assays for viability, biomass, and biofilm matrix. It allows anti-biofilm drug discovery, including the assessment of long-term chemotherapeutic effects.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/54829