Mimicking the Function of Signaling Proteins: Toward Artificial Signal Transduction Therapy
Title:
Mimicking the Function of Signaling Proteins: Toward Artificial Signal Transduction Therapy
Author:
Peri-Naor, Ronny
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (744 seconds)
Series:
Biochemistry
General Note:
Title from resource description page
Abstract:
We present guidelines for developing synthetic 'chemical transducers' that can induce communication between naturally unrelated proteins. In addition, detailed protocols are presented for synthesizing and testing a specific 'transducer' that enables a growth factor to activate a detoxifying enzyme and consequently, to regulate the cleavage of an anticancer prodrug.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/54396