Tracking Drug-induced Changes in Receptor Post-internalization Trafficking by Colocalizational Analysis
Title:
Tracking Drug-induced Changes in Receptor Post-internalization Trafficking by Colocalizational Analysis
Author:
Ong, Edmund
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (468 seconds)
Series:
Biology
General Note:
Title from resource description page
Abstract:
Receptor trafficking modulates signaling and cell responsiveness to ligands and is, itself, responsive to cell conditions, including ligand-induced signaling. Here, we describe a powerful and flexible technique for quantitatively assessing drug-induced receptor trafficking using immunolabeling and colocalizational analysis.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/52824