Aip1p Dynamics Are Altered by the R256H Mutation in Actin
Title:
Aip1p Dynamics Are Altered by the R256H Mutation in Actin
Author:
Pierick, Alyson R.
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (537 seconds)
Series:
Biology
General Note:
Title from resource description page
Abstract:
Disease-causing mutations in actin can alter cytoskeletal function. Cytoskeletal dynamics are quantified through imaging of fluorescently tagged proteins using total internal fluorescence microscopy. As an example, the cytoskeletal protein, Aip1p, has altered localization and movement in cells expressing the mutant actin isoform, R256H.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/51551