RNA Catalyst as a Reporter for Screening Drugs against RNA Editing in Trypanosomes
Title:
RNA Catalyst as a Reporter for Screening Drugs against RNA Editing in Trypanosomes
Author:
Moshiri, Houtan
Personal Author:
Publication Information:
Cambridge, MA MyJoVE Corp 2016
Physical Description:
online resource (559 seconds)
Series:
Biology
General Note:
Title from resource description page
Abstract:
A highly sensitive ribozyme-based assay, applicable to high-throughput screening of chemicals targeting the unique process of RNA editing in trypanosomatid pathogens, is described in this paper. Inhibitors can be used as tools for hypothesis-driven analysis of the RNA editing process and ultimately as therapeutics.
Reading Level:
For undergraduate, graduate, and professional students
Subject Term:
Electronic Access:
https://www.jove.com/t/51712